Viviana Hermosilla Aguayo

Jan 9, 2025 | science.org | Harrison J. Ostridge |Arindam Ghosh |Anqi Wei |Viviana Hermosilla Aguayo

AbstractCartilage is a strong, flexible connective tissue that serves vital support functions in the vertebrate skeletal system. In addition to giving structure to parts of the body, such as the nose, ears, and larynx, cartilage protects bones and joints by absorbing shock and reducing friction (1–3).

Oct 18, 2023 | nature.com | Brandon J. Mannion |Dunja Knapp |Fabian Lim |Anna Czarkwiani |Viviana Hermosilla Aguayo |Licia Selleri | +6 more

AbstractThe cell type-specific expression of key transcription factors is central to development and disease. Brachyury/T/TBXT is a major transcription factor for gastrulation, tailbud patterning, and notochord formation; however, how its expression is controlled in the mammalian notochord has remained elusive. Here, we identify the complement of notochord-specific enhancers in the mammalian Brachyury/T/TBXT gene.