Xinchen Lv

3 weeks ago | tandfonline.com | Xinchen Lv |Wendong Liu |Xue Zhou |Yu Yang

AbstractSystemic autoimmune diseases (SADs) encompass a spectrum of organ involvement, clinical heterogeneity, and therapeutic challenges meriting significant research. These conditions involve the immune system mistakenly attacking and damaging multiple body tissues and organs, leading to chronic inflammation and damage. Exosomes are nanoscale extracellular vesicles secreted by cells that modulate intercellular communication and immunity.

Nov 18, 2024 | mdpi.com | Shuai Zhang |Yu Yang |Xinchen Lv |Xue Zhou

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Oct 23, 2024 | mdpi.com | Shuai Zhang |Yu Yang |Xinchen Lv |Xue Zhou

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.

Oct 2, 2024 | nature.com | Xinchen Lv |Yuanyuan Zhang |Jianhua Luo |Liang Tao

AbstractClostridioides difficile toxin B (TcdB) is the key virulence factor accounting for C. difficile infection-associated symptoms. Effectively neutralizing different TcdB variants with a universal solution poses a significant challenge. Here we present the de novo design and characterization of pan-specific mini-protein binders against major TcdB subtypes.

Oct 27, 2023 | mdpi.com | Shuai Zhang |Yu Yang |Xinchen Lv |Wendong Liu

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessReviewby, , , , , * and * Department of Forensic Medicine, School of Basic Medicine and Biological Sciences, Soochow University, Suzhou 215123, China*Authors to whom correspondence should be addressed. Int. J. Mol. Sci.