Xusheng Wang

Aug 28, 2024 | mdpi.com | Suyuan Zhang |Min Wang |Xusheng Wang |Jun Song

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Aug 15, 2024 | preprints.org | Suyuan Zhang |Min Wang |Xusheng Wang |Jun Song

PreprintReviewVersion 1This version is not peer-reviewedVersion 1: Received: 15 August 2024 / Approved: 15 August 2024 / Online: 15 August 2024 (16:35:25 CEST)Zhang, S.; Wang, M.; Wang, X.; Song, J.; Yang, X. Electrocatalysis in MOF Films for Flexible Electrochemical Sensing: A Comprehensive Review. Preprints 2024, 2024081169. https://doi.org/10.20944/preprints202408.1169.v1Zhang, S.; Wang, M.; Wang, X.; Song, J.; Yang, X.

May 10, 2024 | biorxiv.org | Oluwademilade Nuga |Kristin J. Richardson |Nikhil Patel |Xusheng Wang

AbstractUbiquitin controls many cellular processes via its post-translational conjugation onto substrates. Its use is highly variable due to its ability to form poly-ubiquitin with various topologies. Among them, linear chains have emerged as important regulators of immune responses and protein degradation.

Apr 23, 2024 | nature.com | Xusheng Wang |Chunyu Liu |Junmin Peng

AbstractDeconvolution is an efficient approach for detecting cell-type-specific (cs) transcriptomic signals without cellular segmentation. However, this type of methods may require a reference profile from the same molecular source and tissue type. Here, we present a method to dissect bulk proteome by leveraging tissue-matched transcriptome and proteome without using a proteomics reference panel.

Mar 5, 2024 | biorxiv.org | Shouneng Peng |Erming Wang |Minghui Wang |Xusheng Wang

AbstractINTRODUCTION: The interconnection between brain aging and Alzheimer's disease (AD) remain to be elucidated. METHODS: We investigated multi-omics (transcriptomics and proteomics) data from multiple brain regions (i.e., the hippocampus (HIPP), prefrontal cortex (PFC), and cerebellum (CRBL)) in cognitively normal individuals. RESULTS: We found that brain samples could be divided into ADL (AD-like) and NL (normal) subtypes which were correlated across brain regions.