Analyst

4 days ago | pubs.rsc.org | Elijah Gonzalez |Brian M. Stoltz

Concise Total Synthesis of the Cage-Like Sesquiterpenoid (+)-Daphnepapytone A We report a non-biomimetic total synthesis of (+)-daphnepapytone A, an unprecedented member of the guaiane-derived sesquiterpenoids that displays moderate inhibitory activity against -glycosidase (IC50 = 159 ± 2.1 M) and possesses a highly strained bridging cyclobutane motif.

6 days ago | pubs.rsc.org | Kimberly Zhang |Tianyang Chen |Julius Oppenheim |luming Yang

High-resolution structure of Zn3(HOTP)2 (HOTP = hexaoxidotri-phenylene), a three-dimensional conductive MOF Although two-dimensional (2D) electrically conducting metal-organic frameworks (cMOFs) have become prominent due to their numerous potential applications, their structures are often implied or assumed from rather crude powder X-ray diffrac-tion data.

1 week ago | pubs.rsc.org | Yiwen Chen |Ziyuan Pang |Gege Li |Xiaobo Yang

Alkylaluminium-Catalyzed Regioselective Hydrophosphinylation of α,β-Unsaturated Ketones into γ‑Ketophosphine Oxides A green method for regioselective hydrophosphinylation of α,β-unsaturated ketones using alkylaluminium compounds has been developed. It proceeds without acids, bases, or additives, yielding γ-ketophosphine oxides efficiently. This process offers excellent atom economy, functional group tolerance, and high yields in a short time.

1 week ago | pubs.rsc.org | Joana Ferreira |A. Oliveira |Indústria Farmacêutica |A. Fonseca

Polymeric nanocarriers for cancer treatment: the promise of sensitive poly(2-(diisopropylamino)ethyl methacrylate) Polymeric nanoparticles are extremely valuable carriers for drug/gene delivery to treat cancer, as they can protect different therapeutic agents during blood circulation while being able to deliver them at desired locations.

1 week ago | pubs.rsc.org | Raffaella Demichelis |Blake Armstrong |Paolo Raiteri |Julian Gale

Atomistic insight into the interaction of aspartic acid species with calcium carbonate: model development† The development of models that allow access to atomic-scale information is crucial for expanding our understanding of interfacial processes that enable the formation and growth of biominerals in both abiotic and biogeochemical environments.