BMJ Open Diabetes Research & Care

BMJ Open Diabetes Research & Care

BMJ Open Diabetes Research & Care is an open access journal dedicated to sharing high-quality research on type 1 and type 2 diabetes, along with related complications. The journal accepts only original research and systematic reviews. All submissions undergo a thorough external peer review process to guarantee the publication of reliable and valuable information.

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Diabetes and all-cause mortality among middle-aged and older adults in China, England, Mexico, rural South Africa, and the USA: a population-based study of longitudinal aging cohorts

1 month ago | drc.bmj.com | David Flood |Yuan Zhang |Emma Nichols |Chihua Li

While diabetes has long been associated with increased mortality in high-income countries, contemporary and cross-national estimates of this association have been limited by several factors. We therefore aimed to answer the question of how diabetes impacts all-cause mortality among middle-aged and older adults (aged 51 years or greater) in China, England, Mexico, rural South Africa, and the USA?
Rate and risk factors of kidney function decline among South Asians with type 2 diabetes: analysis of the CARRS Trial

Aug 17, 2024 | drc.bmj.com | Kavita Singh |Dimple Kondal |Ram Jagannathan |MOHAMMED ALI

Epidemiology/Health services research Rate and risk factors of kidney function decline among South Asians with type 2 diabetes: analysis of the CARRS Trial Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
Rate and risk factors of kidney function decline among South Asians with type 2 diabetes: analysis of the CARRS Trial

Aug 1, 2024 | drc.bmj.com | Kavita Singh |Dimple Kondal |Ram Jagannathan |MOHAMMED ALI

Epidemiology/Health services research Rate and risk factors of kidney function decline among South Asians with type 2 diabetes: analysis of the CARRS Trial Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
Environmental Determinants of Islet Autoimmunity (ENDIA) longitudinal prospective pregnancy to childhood cohort study of Australian children at risk of type 1 diabetes: parental demographics and birth information

Jul 16, 2024 | drc.bmj.com | Rebecca Thomson |Helena Oakey |Aveni Haynes |Maria E. Craig

DiscussionWith the ENDIA cohort fully recruited, we report on the cohort’s characteristics in terms of parental demographics, maternal and neonatal outcomes and the distribution of HLA genotypes with respect to T1D proband status. We can now contextualize the ENDIA Study in the broader Australian population and highlight distinctions with other T1D cohorts from early life.
Unveiling potential therapeutic targets for diabetes-induced frozen shoulder through Mendelian randomization analysis of the human plasma proteome

May 7, 2024 | drc.bmj.com | Kun Chen |Tian Tian |Peng Gao |XiaoXiang Fang

Genetics/Genomes/Proteomics/Metabolomics Unveiling potential therapeutic targets for diabetes-induced frozen shoulder through Mendelian randomization analysis of the human plasma proteome Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service.
Circulating metabolomic markers in association with overall burden of microvascular complications in type 1 diabetes

Apr 11, 2024 | drc.bmj.com | Viktor Rotbain Curovic |Brede A Sørland |Tine W. Hansen |Siddhi Jain

MethodsThrough 2009–2011, a total of 667 individuals with T1D exhibiting albuminuria, ranging from normal to severely increased, were recruited from Steno Diabetes Center Copenhagen. Individuals with kidney failure were excluded.
Cost-effectiveness analysis of two interventions to promote physical activity in a multiethnic population at high risk of diabetes: an economic evaluation of the 48-month PROPELS randomized controlled trial

Mar 12, 2024 | drc.bmj.com | Laura Heathcote |Daniel Pollard |Alan Brennan |Melanie J. Davies

WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE, OR POLICYIntroductionIt is estimated that diabetes affects just under half a billion people worldwide, of whom approximately 90% in high-income countries have type 2 diabetes (T2D).1 People with T2D have an elevated risk of developing serious complications such as renal failure, blindness, amputation, cardiovascular disease (CVD), depression, and osteoarthritis.
Cost-effectiveness analysis of two interventions to promote physical activity in a multiethnic population at high risk of diabetes: an economic evaluation of the 48-month PROPELS randomized controlled trial

Mar 1, 2024 | drc.bmj.com | Laura Heathcote |Daniel Pollard |Alan Brennan |Melanie J. Davies

MethodsThis analysis was a lifetime horizon, model-based cost-utility analysis using the School for Public Health Research (SPHR) Diabetes Prevention Model v3.2 (hereafter referred to as “the model”),19 20 as prespecified in the PROPELS health economics analysis plan. A model-based analysis was conducted for two reasons.
Incident dementia risk among patients with type 2 diabetes receiving metformin versus alternative oral glucose-lowering therapy: an observational cohort study using UK primary healthcare records

Jan 25, 2024 | drc.bmj.com | William Doran |Louis Tunnicliffe |Rutendo Muzambi |Christopher T. Rentsch

RESEARCH DESIGN AND METHODSCPRD Gold includes longitudinal primary care records from practices using Vision software covering a large, unselected study population, which is demographically representative of the UK.13 It contains details of symptoms, coded diagnoses, test results, referrals and drug prescriptions.
Impact of sodium-glucose cotransporter 2 inhibitors on cardiovascular outcomes in patients with chronic kidney disease: propensity score matched analysis

Jan 24, 2024 | drc.bmj.com | Wen Sun |Bryan P. Yan

Cardiovascular Diabetes Complications Kidney Failure, Chronic Type 2 diabetes mellitus (T2DM) is the most common cause of chronic kidney disease (CKD).1 Age-adjusted prevalence of CKD in patients with T2DM is approximately 40%, of which majority are mild to moderate.2 The risk gradient of cardiovascular (CV) mortality in CKD increased linearly with decreased glomerular filtration rate (GFR) but changed little when GFR was greater than 75.3 Sodium-glucose cotransporter 2 inhibitors (SGLT2i)...

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