Journal of the American College of Cardiology

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Association of PM2.5 With Cardiac Mechanics Using Speckle-Tracking Echocardiography in the Cardiovascular Health Study:

4 weeks ago | jacc.org | Andrew Chang |Joel D. Kaufman |Annabel Tan |Sanjiv Shah

References1. "Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019". Lancet . 2020;396:1223-1249. 2. "Global association of air pollution and heart failure: a systematic review and meta-analysis". Lancet . 2013;382:1039-1048. 3. "The Cardiovascular Health Study: design and rationale". Ann Epidemiol . 1991;1:263-276. 4.
Fluoropyrimidine Chemotherapy and the Risk of Death and Cardiovascular Events in Patients With Gastrointestinal Cancer:

4 weeks ago | jacc.org | Aderonke T Abiodun |Chengsheng Ju |Catherine Welch |Jennifer Lai

Introduction Fluoropyrimidine chemotherapy agents are used first line in the treatment of many gastrointestinal and other solid organ malignancies globally.1-3 The development of cardiotoxicity can often complicate its use and has various manifestations from asymptomatic electrocardiogram changes to angina, heart failure (HF), myocardial infarction, and sudden cardiac death.4 Baseline cardiovascular disease (CVD) and cardiovascular risk factors are common in patients with gastrointestinal...
Medicine’s Responsibility in Divided Times: Moving Mountains Together

1 month ago | jacc.org | Harlan M. Krumholz

IntroductionWorld history has its cycles. Now, we are experiencing rising tensions among and within countries. Geopolitical issues dominate the news. For some, international travel is becoming fraught. Economic policies are trending toward isolationism, and globalism appears on the decline. Moreover, the pace of change is accelerating.
Heart Failure Care and Outcomes After Private Equity Acquisition of U.S. Hospitals:

1 month ago | jacc.org | Daniel Johnson |Michael Liu |Victoria Bartlett |Zhaonian Zheng

References1. "Monetizing Medicine: Private Equity and Competition in Physician Practice Markets. American Antitrust Institute, Petris Center". Washington Center for Equitable Growth, 2023. 2. "Private equity–acquired physician practices and market penetration increased substantially, 2012–21". Health Aff . 2024;43:3: 354-362. https://doi.org/10.1377/hlthaff.2023.00152. 3. "Changes in hospital adverse events and patient outcomes associated with private equity acquisition". JAMA . 2023;330:24: 2365-2375.
Prognostic Relevance and Lower Limit of the Reference Range of Left Ventricular Global Longitudinal Strain: A Clinical Validation Study

1 month ago | jacc.org | Daniel Morris |Chung-Lieh Hung |Tor Biering-Sørensen |Tatiana Kuznetsova

Introduction Two-dimensional (2D) left ventricular (LV) global longitudinal systolic strain (GLS), with the use of 2D transthoracic speckle-tracking echocardiography (STE), is a sensitive parameter for detecting early or subclinical LV systolic dysfunction, even when left ventricular ejection fraction (LVEF) is preserved.1-3 However, some important issues concerning GLS remain uncertain, such as the cutoff of the lower limit of the reference normal range (LLN) of GLS for each ultrasound...
Assessment of Intraprocedural Automated Arrhythmia Origin Localization System for Localizing Pacing Sites in 3D Space:

1 month ago | jacc.org | Shijie Zhou |John Whitaker |Stanislav Goldberg |Amir Abdel Wahab

References1. "Ventricular tachycardia ablation versus escalation of antiarrhythmic drugs". N Engl J Med . 2016;375:2: 111-121. 2. "Ventricular tachycardia in 3 dimensions". J Am Coll Cardiol . 2020;75:898-900. 3. "Functional pace-mapping responses for identification of targets for catheter ablation of scar-mediated ventricular tachycardia". Circ Arrhythm Electrophysiol . 2012;5:2: 264-272. 4.
Advancing Care in Cardiogenic Shock: Evidence, Innovation, and Commitment

2 months ago | jacc.org | Harlan M. Krumholz

IntroductionCardiogenic shock remains one of the most formidable challenges in cardiovascular medicine, marked by persistently high morbidity and mortality rates despite significant advances in treatment. In recognition of the urgent need for deeper insights and novel therapeutic strategies, JACC is committed to advancing the field through rigorous science, critical evaluations, and expert perspectives.
Featuring Content From Across the JACC Journals:

2 months ago | jacc.org | Harlan M. Krumholz

IntroductionYou may have noticed an important change at JACC. We have started to include content from the JACC Journals in some of our issues. This initiative promotes outstanding content from across the entire JACC portfolio. JACC JournalsJACC is proud to be more than a single journal—we are a dynamic family of 10 exceptional journals, each dedicated to a unique and vital area within cardiovascular medicine.
Kissing Balloon Dilatation of a Transcatheter Mitral Valve Replacement Within an Extra-Large D-Shaped Annuloplasty Ring:

2 months ago | jacc.org | Harish Sharma |Mohsin Ullah |Sagar N Doshi |M. Adnan Nadir

Introduction Valve-in-ring transcatheter mitral valve replacement (TMVR) has emerged as a treatment option for patients with recurrence of mitral regurgitation (MR) after previous mitral annuloplasty who are at prohibitive risk of re-do surgery.1 In the current absence of purpose-built fully percutaneous valves that can be implanted in an annuloplasty ring, TMVR currently involves the implantation of a circular transcatheter heart valve (THV) designed for transcatheter aortic valve...
The Long-Awaited American ACS Guideline: Closer to a Universal Document

2 months ago | jacc.org | Byrne R.A |Coughlan J.J |Valentín Fuster |Bhatt D.L

IntroductionClinical practice guidelines are among the most impactful documents worldwide. Their impact comes not only from the vast readership and extremely high quotation, but more importantly from the undoubtful influence on patient care. The lives of millions of people around the world benefit from implementing the recommendations presented in guidelines.