Journal of the American College of Cardiology

1 month ago | jacc.org | Harlan M. Krumholz

IntroductionWorld history has its cycles. Now, we are experiencing rising tensions among and within countries. Geopolitical issues dominate the news. For some, international travel is becoming fraught. Economic policies are trending toward isolationism, and globalism appears on the decline. Moreover, the pace of change is accelerating.

1 month ago | jacc.org | Daniel Morris |Chung-Lieh Hung |Tor Biering-Sørensen |Tatiana Kuznetsova

Introduction Two-dimensional (2D) left ventricular (LV) global longitudinal systolic strain (GLS), with the use of 2D transthoracic speckle-tracking echocardiography (STE), is a sensitive parameter for detecting early or subclinical LV systolic dysfunction, even when left ventricular ejection fraction (LVEF) is preserved.1-3 However, some important issues concerning GLS remain uncertain, such as the cutoff of the lower limit of the reference normal range (LLN) of GLS for each ultrasound...

1 month ago | jacc.org | Harlan M. Krumholz

IntroductionCardiogenic shock remains one of the most formidable challenges in cardiovascular medicine, marked by persistently high morbidity and mortality rates despite significant advances in treatment. In recognition of the urgent need for deeper insights and novel therapeutic strategies, JACC is committed to advancing the field through rigorous science, critical evaluations, and expert perspectives.

1 month ago | jacc.org | Harlan M. Krumholz

IntroductionYou may have noticed an important change at JACC. We have started to include content from the JACC Journals in some of our issues. This initiative promotes outstanding content from across the entire JACC portfolio. JACC JournalsJACC is proud to be more than a single journal—we are a dynamic family of 10 exceptional journals, each dedicated to a unique and vital area within cardiovascular medicine.

1 month ago | jacc.org | Harish Sharma |Mohsin Ullah |Sagar N Doshi |M. Adnan Nadir

Introduction Valve-in-ring transcatheter mitral valve replacement (TMVR) has emerged as a treatment option for patients with recurrence of mitral regurgitation (MR) after previous mitral annuloplasty who are at prohibitive risk of re-do surgery.1 In the current absence of purpose-built fully percutaneous valves that can be implanted in an annuloplasty ring, TMVR currently involves the implantation of a circular transcatheter heart valve (THV) designed for transcatheter aortic valve...