Journal of the American College of Cardiology

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ASSESSING THE ACCURACY OF SELF-REPORTED CARDIOVASCULAR OUTCOMES: A SYSTEMATIC REVIEW:

3 weeks ago | jacc.org | Anu Vashist |Xiaoya Sun |César Caraballo |Alyssa Grimshaw

Copyright © 2025, American College of Cardiology Foundation. Published by Elsevier on Behalf of The American College of Cardiology Foundation. This is an Open Access Article under the CC BY-NC-ND License (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Interplay of Chronic Kidney Disease and the Effects of Tirzepatide in Patients With Heart Failure, Preserved Ejection Fraction, and Obesity: The SUMMIT Trial

3 weeks ago | jacc.org | Milton Packer |Michael R. Zile |Christopher M. Kramer |Masahiro Murakami

References1. "Predictors of new-onset heart failure: differences in preserved versus reduced ejection fraction". Circ Heart Fail . 2013;6:279-286. 2. "The association of obesity and cardiometabolic traits with incident HFpEF and HFrEF". JACC Heart Fail . 2018;6:701-709. 3. "Evidence supporting the existence of a distinct obese phenotype of heart failure with preserved ejection fraction". Circulation . 2017;136:6-19. 4.
Initial Experience and Bench Validation of the CLEVE Prosthetic Leaflet Modification Procedure During Aortic and Mitral Valve-in-Valve Procedures:

1 month ago | jacc.org | Amar Krishnaswamy |David Meier |Serge C. Harb |Hacina Gill

References1. "Valve-in-surgical-valve with SAPIEN 3 for transcatheter aortic valve replacement based on Society of Thoracic Surgeons Predicted Risk of Mortality". Circ Cardiovasc Interv . 2021;14:e010288. 2. "One-year outcomes of mitral valve-in-valve using the SAPIEN 3 transcatheter heart valve". JAMA Cardiol . 2020;5:1245-1252. 3. "Transcatheter aortic valve replacement of failed surgically implanted bioprostheses: the STS/ACC registry". J Am Coll Cardiol . 2018;72:370-382. 4.
Preprints: A Revolution in Cardiovascular Science

2 months ago | jacc.org | Harlan M. Krumholz |Joshua D. Wallach

IntroductionScientific publishing is transforming, and preprints are leading the charge. Preprints enhance the rapid communication of discoveries and insights by allowing researchers to share completed work before peer review. This approach complements peer review, which retains its importance, fostering collaboration and accelerating scientific progress.
Articulating the JACC Journals' Direction in Times of Global Change:

2 months ago | jacc.org | Harlan M. Krumholz |Biykem Bozkurt |Y. Chandrashekhar |Bonnie Ky

JACC Journals › JACC › Archives › Just Accepted JACC. . Epublished DOI: 10.1016/j.jacc.2025.02.006FiguresReferencesRelatedDetails InformationCopyright © 2025, American College of Cardiology Foundation. Published by Elsevier Article History ReceivedFebruary 3, 2025AcceptedFebruary 3, 2025Published onlineFebruary 12, 2025
TAVR and Strokes: Are Aortic Atheromas Part of the Story?

2 months ago | jacc.org | Kush Patel |Andreas Baumbach

IntroductionStrokes are often the most feared complication for patients undergoing transcatheter aortic valve replacement (TAVR). They are associated with increased mortality and morbidity, impose significant challenges for family and caregivers, and weigh heavily on healthcare systems. Multiple trials have evaluated the safety and efficacy of cerebral embolic protection devices (CEPDs) and anticoagulation regimes to reduce the incidence of TAVR-related stroke.
Atrial Fibrillation Burden on a 14-Day ECG Monitor: Findings From the GUARD-AF Trial Screening Arm

Jan 1, 2025 | jacc.org | Daniel E. Singer |Steven J. Atlas |Alan S. Go |Steven A. Lubitz

Introduction Recent trials of one-time brief electrocardiographic (ECG) screening for atrial fibrillation (AF) have not shown a significant increase in diagnosed AF compared to usual care.1–3 By contrast, longer-term continuous ECG monitoring detected substantially more AF cases, primarily paroxysmal atrial fibrillation (PAF).4-7 By identifying and treating AF earlier, the goal of screening is to reduce the risk of future cardiovascular events, primarily ischemic stroke.8,9 Although the...
Advancing Prevention: Insights From JACC's Focus Issue

Dec 2, 2024 | jacc.org | Harlan M. Krumholz

IntroductionEach year, cardiovascular disease claims millions of lives worldwide—deaths that are largely preventable. As we present this issue of JACC focused on prevention, we confront unprecedented opportunities and challenges in cardiovascular medicine. The breadth of research in this issue illustrates the dynamic evolution of cardiovascular prevention, from novel therapeutic approaches to troubling implementation gaps.
Uric Acid and SGLT2 Inhibition With Empagliflozin in Heart Failure With Preserved Ejection Fraction: The EMPEROR-Preserved Trial

Dec 1, 2024 | jacc.org | Wolfram Doehner |Stefan Anker |Javed Butler |Faiez Zannad

References1. "Relation of serum uric acid levels and outcomes among patients hospitalized for worsening heart failure with reduced ejection fraction (from the efficacy of vasopressin antagonism in heart failure outcome study with tolvaptan trial)". Am J Cardiol . 2014;114:1713-1721. 2. "Uric acid and survival in chronic heart failure: validation and application in metabolic, functional, and hemodynamic staging". Circulation . 2003;107:1991-1997. 3.
Semaglutide Improves Cardiovascular Outcomes in Patients With History of Coronary Artery Bypass Graft and Obesity:

Nov 18, 2024 | jacc.org | Subodh Verma |Scott Emerson |Jorge Plutzky |Steven Kahn

Semaglutide Improves Cardiovascular Outcomes in Patients With History of Coronary Artery Bypass Graft and ObesitySign in, Subscribe, or Pay to View