Nature Reviews Cardiology

Nature Reviews Cardiology aspires to be the leading platform for reviews and insights tailored for both the scientific and clinical sectors that we support. Our goal is to share articles that are not only authoritative but also easy to read, complemented by clear figures, tables, and other visual elements. We aim to deliver exceptional service to authors, reviewers, and readers alike, putting in the effort to enhance the usefulness and impact of every piece we publish. The journal features a variety of content, including Research Highlights, Comments, News & Views, Reviews, Consensus Statements, and Perspectives that cater to practicing cardiologists and cardiovascular researchers. Our wide-ranging focus ensures that the articles we publish connect with a diverse audience.

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Landmark air-pollution lab under threat from Trump cuts - can it be saved?

2 days ago | nature.com | Jeff Tollefson

A US laboratory that has been instrumental in documenting the impact of air pollution on human health is being shut down by the administration of US President Donald Trump. Scientists are rallying to save it.
How to delight your future boss at a science job interview

2 days ago | nature.com | Julie Gould

Should you tailor your job interview style based on the age, gender and cultural background of the person asking the questions? Margot Smit and Dietmar Hutmacher compare their approaches to hiring and how generational influences might shape how they respond to candidates.
Rare ‘spider star’ spotted consuming its companion

3 days ago | nature.com | Davide Castelvecchi

Astronomers at the world’s largest telescope have found hints of a ‘missing link’ in the evolution of two binary stars that are tightly orbiting one another. It is a long-theorized type of system in which a rapidly spinning neutron star called a pulsar — the remnants of a massive supernova — is engulfed into its larger companion, then stripped it to its core.
Cell trajectory modulation: rapid microfluidic biophysical profiling of CAR T cell functional phenotypes - Nature Communications

3 days ago | nature.com | Kerwin Kwek Zeming |Michael Birnbaum

AbstractChimeric Antigen Receptor (CAR) T cell therapy is a pivotal treatment for hematological malignancies. However, CAR T cell products exhibit batch-to-batch variability in cell number, quality, and in vivo efficacy due to donor-to-donor heterogeneity, and pre/post-manufacturing processes, and the manufacturing of such products necessitates careful testing, both post-manufacturing and pre-infusion.
‘Landmark’ evolution study shows how rice inherits tolerance to cold without DNA changes

3 days ago | nature.com | Smriti Mallapaty

Rice plants can inherit tolerance to cold without changes to their genomes, according to a decade-long study1 carried out by researchers in China. The work, published in Cell today, strengthens the evidence for a form of evolution in which environmental pressures induce heritable changes that do not alter an organism’s DNA.
Why space exploration must not be left to a few powerful nations

3 days ago | nature.com | Brad Tucker

The space industry is expanding fast — and its value is set to triple in the next decade, from US$630 billion in 2023 to $1.8 trillion by 2035. However, although the number of nations with space programmes is growing — with 77 space agencies worldwide — many others are excluded. In particular, many low- and middle-income countries (LMICs), Indigenous Nations and communities and small states are missing from debates around space activities.
LDL-cholesterol lowering with obicetrapib - Nature Reviews Cardiology

3 days ago | nature.com | Gregory B. Lim

In two clinical trials presented at the European Atherosclerosis Society Congress 2025, treatment with the cholesteryl ester transfer protein (CETP) inhibitor obicetrapib in addition to background lipid-lowering therapy significantly reduced plasma LDL-cholesterol (LDL-C) levels. A large, phase III clinical trial is ongoing to test the effects of obicetrapib on cardiovascular outcomes.
Publisher Correction: Ageing limits stemness and tumorigenesis by reprogramming iron homeostasis - Nature

3 days ago | nature.com | Xueqian Zhuang |Alexander Ferrena |David Humphreys |Melissa Blum |Yingqian A Zhan |Yang Zhao | +10 more

Correction to: Nature https://doi.org/10.1038/s41586-024-08285-0 Published online 4 December 2024In the version of the article initially published, the “Transferrin” inset image in Fig. 5b was missing and has now been included in the HTML and PDF versions of the article. About this articleZhuang, X., Wang, Q., Joost, S. et al. Publisher Correction: Ageing limits stemness and tumorigenesis by reprogramming iron homeostasis. Nature (2025).
Associations of climatic factors with pregnancy loss in Nicosia, Cyprus - Journal of Exposure Science & Environmental Epidemiology

3 days ago | nature.com | Aashna Shah

AbstractWhile ambient climatic factors are linked to adverse pregnancy outcomes, only a few studies examine the risk of pregnancy loss. This study aims to examine the effects of climatic factors on pregnancy loss in Nicosia, Cyprus, an area that is highly affected by climate change.
Inequality in infrastructure access and its association with health disparities - Nature Human Behaviour

3 days ago | nature.com | Ying Tu |Bin Lin Chen |Chuan Liao |Shengbiao Wu |Chen Lin |Peng Gong

AbstractEconomic, social and environmental infrastructure forms a fundamental pillar of societal development. Ensuring equitable access to infrastructure for all residents is crucial for achieving the Sustainable Development Goals, yet knowledge gaps remain in infrastructure accessibility and inequality and their associations with human health.