Ana Francisca Vega
Journalist at MVS Noticias
periodista | politóloga | animalista | @MVSNoticias | @elpaismexico | escribí #MexicanosComoYo y #CorazónDeMexicanosComoYo | @CIDE_MX y @StAntsCollege |🇲🇽🇨🇱
Articles
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Nov 6, 2024 |
nature.com | Joan Röhl |Johanna Schleutker |Kenneth Muir |Henrik Grönberg |Nora Pashayan |Demetrius Albanes | +20 more
AbstractGenetic variation at the 19q13.3 KLK locus is linked with prostate cancer susceptibility in men. The non-synonymous KLK3 single nucleotide polymorphism (SNP), rs17632542 (c.536 T > C; Ile163Thr-substitution in PSA) is associated with reduced prostate cancer risk, however, the functional relevance is unknown. Here, we identify that the SNP variant-induced change in PSA biochemical activity mediates prostate cancer pathogenesis.
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Nov 9, 2023 |
nature.com | Thomas Sellers Jr. |David Hunter |Ian Thompson |Robert Hamilton |Ana Francisca Vega |Eric A. Klein | +98 more
The transferability and clinical value of genetic risk scores (GRSs) across populations remain limited due to an imbalance in genetic studies across ancestrally diverse populations. Here we conducted a multi-ancestry genome-wide association study of 156,319 prostate cancer cases and 788,443 controls of European, African, Asian and Hispanic men, reflecting a 57% increase in the number of non-European cases over previous prostate cancer genome-wide association studies. We identified 187 novel risk variants for prostate cancer, increasing the total number of risk variants to 451. An externally replicated multi-ancestry GRS was associated with risk that ranged from 1.8 (per standard deviation) in African ancestry men to 2.2 in European ancestry men. The GRS was associated with a greater risk of aggressive versus non-aggressive disease in men of African ancestry (P = 0.03). Our study presents novel prostate cancer susceptibility loci and a GRS with effective risk stratification across ancestry groups. A multi-ancestry genome-wide association study of prostate cancer performed in 156,319 cases and 788,443 controls identifies 187 novel risk variants associated with the disease. Genetic risk scores associated with overall risk, and risk of aggressive disease in men of African ancestry.
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Apr 19, 2023 |
nature.com | Ana Francisca Vega |Maria García
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Oct 5, 2022 |
nature.com | Daniel Barnes |Austin L. Miller |Ana Francisca Vega
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#Guadalajara ayudemos a Norris!
#Guadalajara https://t.co/RniKvbHSa6
Y sí, lo creo fervientemente. Tenemos que reconstruir puentes de diálogo y no asumir acríticamente el lenguaje que han buscado imponernos. Sin diálogo no hay democracia. ¡Gracias por la invitación @OnexpoNacional!
"No somos fifís vs chairos, solo somos mexicanos que pensamos distinto" afirmó #AnaFranciscaVega #EnConferencia para @OnexpoNacional. #AllenamentiEnCDMX https://t.co/rHKGg51Mu2
Muchas gracias por la invitación @onexpo para platicar sobre oportunidades y desafíos de México en un contexto de incertidumbre. ¡Hasta pronto!
Agradecemos a @anafvega por su enriquecedora plática durante la Asamblea General Ordinaria, con el tema "México entre la obsolescencia y el potencial de crecimiento", en el formato de #OnexpoTalks. https://t.co/9TOkKcu5k9
