Bradley F. Boeve

Jun 15, 2024 | thelancet.com | S List |Bradley F. Boeve |Albert A. Davis

We applaud the proposed research criteria for synucleinopathy—ie, the neuronal α-synuclein disease integrated staging system1Simuni T Chahine LM Poston K et al. A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research. and the SynNeurGe research diagnostic criteria. 2Höglinger GU Adler CH Berg D et al. A biological classification of Parkinson's disease: the SynNeurGe research diagnostic criteria.

Apr 12, 2024 | nature.com | Christopher Schwarz |Eric C Westman |Barbara Segura |Bradley F. Boeve |Dag Aarsland |Annegret Habich

AbstractSex differences permeate many aspects of dementia with Lewy bodies (DLB), yet sex differences in patterns of neurodegeneration in DLB remain largely unexplored. Here, we test whether grey matter networks differ between sexes in DLB and compare these findings to sex differences in healthy controls. In this cross-sectional study, we analysed clinical and neuroimaging data of patients with DLB and cognitively healthy controls matched for age and sex.

Apr 2, 2024 | nature.com | Christopher Schwarz |Matthew L. Senjem |Dennis W. Dickson |Bradley F. Boeve

AbstractDementia with Lewy bodies (DLB) is a neurodegenerative condition often co-occurring with Alzheimer’s disease (AD) pathology. Characterizing white matter tissue microstructure using Neurite Orientation Dispersion and Density Imaging (NODDI) may help elucidate the biological underpinnings of white matter injury in individuals with DLB.