Emma D'Agostino

2 months ago | digitalcommons.library.tmc.edu | Suzanne G. Mays |Emma D'Agostino |Autumn R. Flynn |Xiangsheng Huang

KeywordsAnimals, Colitis, Ligands, Mice, Phospholipids, Receptors, Cytoplasmic and Nuclear, Phospholipid, LRH-1, nuclear receptor, agonist, ulcerative colitisAbstractPhospholipids are ligands for nuclear hormone receptors (NRs) that regulate transcriptional programs relevant to normal physiology and disease. Here, we demonstrate that mimicking phospholipid-NR interactions is a robust strategy to improve agonists of liver receptor homolog-1 (LRH-1), a therapeutic target for colitis.

Jan 23, 2025 | abc.net.au | Emma D'Agostino

The Australian pig industry hopes work to develop a vaccine to protect its animals against Japanese encephalitis virus can be expedited. There is no animal vaccine registered for use in Australia to protect pigs from the mosquito-borne disease. Researchers and Australian Pork Limited say there is an urgent need for a JEV vaccine for pigs, and are appealing to the regulator for support.

Jan 20, 2025 | abc.net.au | Emma Field |Emma D'Agostino

A virus threatening Australia's tomato industry has been detected in a Victorian crop. Tomato brown rugose fruit virus spread from South Australia to a glasshouse in the Goulburn Valley. Victorian authorities are confident the virus has been contained and are now trying to eradicate it. A foreign plant virus that has wreaked havoc on South Australia's tomato industry has been detected in Victoria for the first time.

Jan 10, 2025 | abc.net.au | Emma D'Agostino

Firefighters battling the blaze in Victoria's Grampians National Park say mobile phone reception on the fireground is "nearly non-existent". Despite asking for a temporary boost to coverage in the area, they say it never came. The federal government says improving telecommunications resilience is a priority. Firefighters battling the blaze in the Grampians/Gariwerd National Park say they requested an urgent boost to mobile phone services, but it never came.

Jan 6, 2025 | abc.net.au | Emma D'Agostino |Jane McNaughton

A regional Victorian tomato and zucchini farmer has quit the industry in protest over farmgate prices. He said the discrepancy between what farmers are paid and what the product retails for is pushing people out of the industry. The new Food and Grocery Code of Conduct, aimed to restore the power imbalance faced by farmers from supermarkets, comes into effect in April. To say that Ross Marsolino has had a gutful is probably underselling it.