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Jan 19, 2025 | 
link.springer.com | Universitätsklinikum Erlangen |Friedrich-Alexander-Universität Erlangen-Nürnberg |Deutsches Zentrum Immuntherapie
ZusammenfassungDie Pathophysiologie chronisch-entzündlicher Darmerkrankungen (CED) ist nicht vollständig geklärt. In einem Stufenmodell der European Crohn’s and Colitis Organisation (ECCO) zur Krankheitsentstehung wird von einem Risikopersonenkollektiv ausgegangen, in dem sich über subtile Veränderungen im Verlauf die Erkrankung manifestiert. Zusammenfassung des aktuellen Erkenntnisstands zur Pathophysiologie, Prädiktion und Prävention von CED. Selektive Literaturrecherche via PubMed.
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Nov 24, 2024 | 
bmcpregnancychildbirth.biomedcentral.com | Friedrich-Alexander-Universität Erlangen-Nürnberg |Friedrich-Alexander- Erlangen-Nürnberg
This work aimed to analyze pregnancy app features, expert guidance and content trustworthiness, commercialization, and their user perception. For this purpose, we reviewed app descriptions, performed in-depth searches, and used NLP on user reviews. This section will discuss key findings in the respective areas, derive overall implications, provide insights for clinical practice, limitations of this work, and lastly provide links for future research.
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Nov 19, 2024 | 
trialsjournal.biomedcentral.com | Friedrich-Alexander-Universität Erlangen-Nürnberg
The study is designed as a randomized controlled, single-center, and single-blinded trial, in which participants will be randomly assigned to one of two intervention groups (rumination vs. self-compassion) or a control condition (see “Randomization”) with an allocation ratio of 1:1:1.
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Nov 13, 2024 | 
link.springer.com | Friedrich-Alexander-Universität Erlangen-Nürnberg
AbstractThe prevention of preterm birth is a challenging task for obstetricians. Cervical cerclage, used as both a primary and secondary prevention method for spontaneous preterm birth, is a crucial surgical intervention. It is essential that obstetricians can learn this procedure in a simulated environment before performing the stitches on high-risk patients. This study aimed to develop a simulator based on 3D printing and evaluate its validity for clinical training.
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Oct 23, 2024 | 
journals.plos.org | Meike Janssen |GeoZentrum Nordbayern |Friedrich-Alexander-Universität Erlangen-Nürnberg |Luca Caracciolo
Loading metrics Open Access Peer-reviewedResearch Article Citation: Janssen M, Caracciolo L, Bonnell LM, Lander RH, Adelhardt P, Moldenhauer L, et al. (2024) From loose sand to sandstone: An experimental approach on early calcite precipitation in sands of siliciclastic and mixed carbonate-siliciclastic composition. PLoS ONE 19(10): e0312479.
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Oct 16, 2024 | .html&sz=64)
fis.tu-dresden.de | Eckart Kunze |Michael Franz |Friedrich-Alexander-Universität Erlangen-Nürnberg |Ron Luft
The integration of fiber reinforced polymers and novel lightweight design strategies in aircraft interiors offers the potential to reduce the empty take-off weight of commercial aircraft and thus decrease CO2 emissions during operation. In order to meet the mechanical requirements of high load-bearing inserts in sandwich structures, effective distribution of localized forces across the face sheets is crucial.
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Sep 26, 2024 | 
molecular-cancer.biomedcentral.com | Humboldt-Universität zu Berlin |Friedrich-Alexander-Universität Erlangen-Nürnberg |Friedrich-Alexander- Erlangen-Nürnberg |Anselm H.C
M. Krumbholz: conception and design, performed research, data analysis, writing-original draft, and writing-review and editing. A. Dolnik: conception and design, research, data analysis, and writing-review and editing. E. Sträng: data analysis and editing. T. Ghete: data analysis and editing, writing-review and editing. S. Skambraks: research and editing. S. Hutter: data analysis and editing. A. Simonis: research and writing-review and editing. F.
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Sep 19, 2024 | 
trialsjournal.biomedcentral.com | Friedrich-Alexander-Universität Erlangen-Nürnberg |Kantonsspital Winterthur
The SCG could be seen as standard care, because the participants will receive health lectures and light stretching exercises at the same frequency as the IG. All biological specimen will be collected and analyzed at the same time points in both groups. The general study design is that of a randomized controlled trial.
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Sep 9, 2024 | 
bmcpsychiatry.biomedcentral.com | Friedrich-Alexander-Universität Erlangen-Nürnberg
ReferencesSenaratna CV, Perret JL, Lodge CJ, Lowe AJ, Campbell BE, Matheson MC, et al. Prevalence of obstructive sleep apnea in the general population: a systematic review. Sleep Med Rev. 2017;34:70–81. PubMed Google Scholar Fietze I, Laharnar N, Obst A, Ewert R, Felix SB, Garcia C, et al. Prevalence and association analysis of obstructive sleep apnea with gender and age differences - results of SHIP-Trend. J Sleep Res. 2019;28(5):e12770.
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Aug 13, 2024 | 
link.springer.com | Friedrich-Alexander-Universität Erlangen-Nürnberg |Deutsches Zentrum Immuntherapie |Humboldt-Universität zu Berlin
AbstractPathogenic variants in the Cu/Zn superoxide dismutase (SOD1) gene can be detected in approximately 2% of sporadic and 11% of familial amyotrophic lateral sclerosis (ALS) patients in Europe. We analyzed the clinical phenotypes of 83 SOD1-ALS patients focusing on patients carrying the most frequent (likely) pathogenic variants (R116G, D91A, L145F) in Germany. Moreover, we describe the effect of tofersen treatment on ten patients carrying these variants.
