Hong Wei

Dec 9, 2024 | nature.com | Zhong Lin Wang |Guohao Yuan |Wei Yan |Kai Yuan |Yanping Bao |Jie Shi | +3 more

AbstractSleep interacts reciprocally with the gut microbiota. However, mechanisms of the gut microbe-brain metabolic axis that are responsible for sleep behavior have remained largely unknown. Here, we showed that the absence of the gut microbiota can alter sleep behavior. Sleep deprivation reduced butyrate levels in fecal content and the hypothalamus in specific pathogen-free mice but not in germ-free mice.

May 3, 2024 | respiratory-research.biomedcentral.com | Hong Wei

The virus used in this study was Pandemic Influenza A/California/04/2009 (CA04) virus, which was kindly provided by Dr. Kevin Harrod from University of Alabama at Birmingham. The virus was propagated in Madin-Darby canine kidney (CCL-34, MDCK, ATCC, Manassas, VA) cells, as previously published [27,28,29,30,31], and tittered by quantitative plaque assay using MDCK cells [29].

Nov 27, 2023 | mdpi.com | Hong Wei |Wen Dai |Bo Wang |Hui Zhu

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Sep 29, 2023 | frontiersin.org | Hamid Reza |Hong Wei

Hamid Reza Nouri1 Niccolette Schaunaman1 Monica Kraft2 Liwu Li3 Mari Numata-Nakamura1 Hong Wei Chu1* 1Department of Medicine, National Jewish Health (United States), United States 2Department of Medicine, Icahn School of Medicine at Mount Sinai, United States 3Department of Biological Sciences, College of Science, Virginia Tech, United States The final, formatted version of the article will be published soon.

Sep 4, 2023 | paperity.org | Hong Wei

Cellular and Molecular Neurobiology, Aug 2023 Heterozygous mutations affecting FOXJ1, a transcription factor governing multiciliated cell development, have been associated with obstructive hydrocephalus in humans. However, factors that disrupt multiciliated ependymal cell function often cause communicating hydrocephalus, raising questions about whether FOXJ1 mutations cause hydrocephalus primarily by blocking cerebrospinal fluid (CSF) flow or by different mechanisms.