Odette Laneuville

Jun 11, 2024 | nature.com | Eliah G. Overbey |JangKeun Kim |Braden T. Tierney |Jiwoon Park |Deena Najjar |Remi Klotz | +30 more

AbstractSpaceflight induces molecular, cellular, and physiological shifts in astronauts and poses myriad biomedical challenges to the human body, which are becoming increasingly relevant as more humans venture into space1-6. Yet, current frameworks for aerospace medicine are nascent and lag far behind advancements in precision medicine on Earth, underscoring the need for rapid development of space medicine databases, tools, and protocols.

Mar 1, 2024 | jrheum.org | T. Mark Campbell |Odette Laneuville |Guy Trudel |T.M. Campbell

Key Indexing Terms:cartilageknee jointmagnetic resonance imagingosteoarthritisrange of motionOsteoarthritis (OA) is the most common form of arthritis, and the knee is the most commonly affected large joint.1 At present, no OA disease-modifying antirheumatic drugs exist, and treatment is palliative.2 With the aging population, OA prevalence is ever-increasing1,2; therefore, novel approaches for knee OA treatment are desperately needed.

Dec 11, 2023 | jrheum.org | T. Mark Campbell |Odette Laneuville |Guy Trudel |T.M. Campbell

People with knee OA and flexion contracture developed localized tibial articular cartilage loss: data from the osteoarthritis initiative T. Mark Campbell, Odette Laneuville, Guy Trudel The Journal of Rheumatology Dec 2023, jrheum.2023-0743; DOI: 10.3899/jrheum.2023-0743

Aug 9, 2023 | nature.com | Tammy Liu |Gerd Melkus |Tim Ramsay |Odette Laneuville

AbstractSpace travel requires metabolic adaptations from multiple systems. While vital to bone and blood production, human bone marrow adipose (BMA) tissue modulation in space is unknown. Here we show significant downregulation of the lumbar vertebrae BMA in 14 astronauts, 41 days after landing from six months’ missions on the International Space Station. Spectral analyses indicated depletion of marrow adipose reserves. We then demonstrate enhanced erythropoiesis temporally related to low BMA.

Jul 2, 2023 | onlinelibrary.wiley.com | Odette Laneuville |Emily Standen |Haodong Zhou |Cassandra M. Donatelli

1 INTRODUCTION Mudskippers are a group of amphibious fishes in the family Oxudercidae, with various species that live across a wide range of terrestrial and aquatic habitats.