Rhys Grinter

May 25, 2024 | nature.com | Curtis Cottam |Rhys White |Lauren Beck |Christopher Stewart |Scott A. Beatson |Rhys Grinter

AbstractVirulence and metabolism are often interlinked to control the expression of essential colonisation factors in response to host-associated signals. Here, we identified an uncharacterised transporter of the dietary monosaccharide ʟ-arabinose that is widely encoded by the zoonotic pathogen enterohaemorrhagic Escherichia coli (EHEC), required for full competitive fitness in the mouse gut and highly expressed during human infection.

Apr 15, 2024 | nature.com | Pok Man Leung |Rhys Grinter |Eve Tudor-Matthew |Carlo R. Carere |Matthew Stott |Ralf B. Schittenhelm

AbstractDiverse aerobic bacteria use atmospheric hydrogen (H2) and carbon monoxide (CO) as energy sources to support growth and survival. Such trace gas oxidation is recognised as a globally significant process that serves as the main sink in the biogeochemical H2 cycle and sustains microbial biodiversity in oligotrophic ecosystems. However, it is unclear whether archaea can also use atmospheric H2.