Robert Petersen

Los Angeles

Host and Producer at The Hidden History of Los Angeles

Host and producer of the Hidden History of Los Angeles podcast. [email protected]

Articles

Angiopoietin-like protein 8 directs DNA damage responses towards apoptosis by stabilizing PARP1-DNA condensates - Cell Death & Differentiation

Nov 26, 2024 | nature.com | Jing Yang |Robert Petersen |Ling Zheng |Yu ZHANG

AbstractUpon genotoxic stresses, cells employ various DNA damage responses (DDRs), including DNA damage repair or apoptosis, to safeguard genome integrity. However, the determinants among different DDRs choices are largely unknown. Here, we report angiopoietin-like protein 8 (ANGPTL8), a secreted regulator of lipid metabolism, localizes to the nucleus and acts as a dynamic switch that directs DDRs towards apoptosis rather than DNA repair after genotoxin exposure.
In Your Opinion: Support Cuozzo and Ganta for County Commissioner – The Franklin Reporter & Advocate

Oct 22, 2024 | franklinreporter.com | Robert Petersen |Bill Bowman

By Robert Petersen. County governments control a significant portion of our property tax bill, and with property taxes already sky-high, it’s critical that those dollars are spent wisely. Unfortunately, under the leadership of Democrat Party Chair Peg Schaffer, the current Somerset County Commissioners appear more focused on rewarding political insiders than being responsible stewards of our tax dollars.
β-synuclein regulates the phase transitions and amyloid conversion of α-synuclein - Nature Communications

Oct 8, 2024 | nature.com | Yuchen chen |Robert Petersen |Xiang Cheng |Yanxun V. Yu |Ling Zheng |Hong Zhou Chen

AbstractParkinson’s disease (PD) and Dementia with Lewy Bodies (DLB) are neurodegenerative disorders characterized by the accumulation of α-synuclein aggregates. α-synuclein forms droplets via liquid-liquid phase separation (LLPS), followed by liquid-solid phase separation (LSPS) to form amyloids, how this process is physiologically-regulated remains unclear. β-synuclein colocalizes with α-synuclein in presynaptic terminals.
Altered dynamic functional network connectivity in drug-naïve Parkinson’s disease patients with excessive daytime sleepiness

Dec 6, 2023 | frontiersin.org | Robert Petersen |Ane Murueta-Goyena |Keisuke Suzuki

IntroductionParkinson’s disease (PD) is the second most common neurodegenerative disease, with more than 8.5 million individuals suffering from PD worldwide (Grover et al., 2022). Excessive daytime sleepiness (EDS) is a frequent nonmotor symptoms in PD patients, affecting up to 20–60% of PD patients (Liu et al., 2022). EDS mainly manifests as the inability to stay awake and alert during typical waking periods, leading to unintended lapses into drowsiness or sleep states (Liu et al., 2022).
Jack Parsons HHLA83 on Apple Podcasts

Oct 9, 2023 | podcasts.apple.com | Robert Petersen

This episode tells the remarkable and strange story of Jack Parsons, one of the founders of the Jet Propulsion Laboratory.
Josh Nelson: LA Stories: Live at Sam First

Oct 4, 2023 | allaboutjazz.com | Robert Petersen

Home » Jazz Articles » Josh Nelson: LA Stories: Live at Sam First Liner NotesLA Stories: Live at Sam First was recorded in February 2022 at Sam First, which has quickly become the heartbeat of L.A.'s jazz community. With this album, Nelson continues a love letter to Los Angeles he began with his 2017 release, The Sky Remains, which was part of his Discovery Project multimedia series. In a city where history is too often forgotten, Nelson puts it center stage.
Differential spatiotemporal gait effects with frequency and dopaminergic modulation in STN-DBS

Sep 1, 2023 | frontiersin.org | Feinstein Institutes |Robert Petersen |Robert LeMoyne |Jana Seuthe

Introduction Advanced Parkinson's disease (PD) produces characteristic gait changes that include reduced stride length (Morris et al., 1996, 1998), decreased velocity (Galna et al., 2015), shuffling, multistep turning, and freezing of gait (Okuma, 2014).
Frontiers | Subthalamic deep brain stimulation for primary dystonia: defining an optimal location using the medial subthalamic nucleus border as anatomical reference

Jul 21, 2023 | frontiersin.org | Robert Petersen |Atsushi Nambu |Stephen Tisch

1. Introduction Dystonia is a movement disorder characterized by sustained or intermittent muscle contractions that result in abnormal movements and/or posture (Balint and Bhatia, 2014). Treatment is challenging because of dystonia’s highly complex etiology and pathogenesis (Batla et al., 2012; Balint et al., 2018; Albanese et al., 2019).
Frontiers | Machine learning models for diagnosis and prognosis of Parkinson's disease using brain imaging: general overview, main challenges, and future directions

Jul 19, 2023 | frontiersin.org | Garcia Santa Cruz |Robert Petersen |Carmen Jiménez-Mesa |Diego Castillo-Barnes

Beatriz Garcia Santa Cruz1*, Andreas Husch2 and Frank Hertel1 1National Department of Neurosurgery, Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg 2Imaging AI Group, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg Parkinson's disease (PD) is a progressive and complex neurodegenerative disorder associated with age that affects motor and cognitive functions.
A renal YY1-KIM1-DR5 axis regulates the progression of acute kidney injury - Nature Communications

Jul 17, 2023 | nature.com | Yuchen chen |Robert Petersen |Hong Zhou Chen |Kun Huang

AbstractAcute kidney injury (AKI) exhibits high morbidity and mortality. Kidney injury molecule-1 (KIM1) is dramatically upregulated in renal tubules upon injury, and acts as a biomarker for various renal diseases. However, the exact role and underlying mechanism of KIM1 in the progression of AKI remain elusive. Herein, we report that renal tubular specific knockout of Kim1 attenuates cisplatin- or ischemia/reperfusion-induced AKI in male mice.

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Robert Petersen @lahiddenhistory

16 Oct 24

RT @HUSC_ICW: 🎙️🎧Podcast x Podcast! Thanks to the @lahiddenhistory podcast for interviewing ICW's Bill Deverell about our podcast, Western…

Robert Petersen @lahiddenhistory

31 Oct 23

RT @LAhistory: “On Halloween in 1936, a group of men gathered in the Arroyo Seco in Pasadena to conduct an experiment." @LAHiddenHistory’s…

Robert Petersen @lahiddenhistory

19 Oct 23

Learn all about the upcoming L.A. Archives Bazaar in the latest episode of the podcast. https://t.co/R4mpHgVf3s

Robert Petersen

Articles

Angiopoietin-like protein 8 directs DNA damage responses towards apoptosis by stabilizing PARP1-DNA condensates - Cell Death & Differentiation

In Your Opinion: Support Cuozzo and Ganta for County Commissioner – The Franklin Reporter & Advocate

β-synuclein regulates the phase transitions and amyloid conversion of α-synuclein - Nature Communications

Altered dynamic functional network connectivity in drug-naïve Parkinson’s disease patients with excessive daytime sleepiness

Jack Parsons HHLA83 on Apple Podcasts

Josh Nelson: LA Stories: Live at Sam First

Differential spatiotemporal gait effects with frequency and dopaminergic modulation in STN-DBS

Frontiers | Subthalamic deep brain stimulation for primary dystonia: defining an optimal location using the medial subthalamic nucleus border as anatomical reference

Frontiers | Machine learning models for diagnosis and prognosis of Parkinson's disease using brain imaging: general overview, main challenges, and future directions

A renal YY1-KIM1-DR5 axis regulates the progression of acute kidney injury - Nature Communications

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