Stefan Günther

2 months ago | nzz.ch | Stefan Günther

Andrew Harnik / GettyIn Washington ist eine Maschine der Fluggesellschaft American Airlines in den Potomac River gestürzt. Das Flugzeug ist beim Landeanflug auf den Ronald-Reagan-Flughafen mit einem Helikopter zusammengestossen. Stefan Günther 30.01.2025, 09.15 Uhr 1 min Muriel Bowser, die Bürgermeisterin von Washington, spricht an einer Pressekonferenz über die Rettungsmassnahmen. Anadolu Ambulanzen und Feuerwehr versammeln sich am Ronald-Reagan-Flughafen. Im Hintergrund das Capitol.

Jan 7, 2025 | nature.com | Sheng Wang |Carsten Kuenne |Stefan Günther |Nina Wettschureck |Young-June Jin |Mohamad Wessam Alnouri

AbstractAtherosclerotic lesions develop preferentially in arterial regions exposed to disturbed blood flow, where endothelial cells acquire an inflammatory phenotype. How disturbed flow induces endothelial cell inflammation is incompletely understood. Here we show that histone H3.3 phosphorylation at serine 31 (H3.3S31) regulates disturbed-flow-induced endothelial inflammation by allowing rapid induction of FOS and FOSB, required for inflammatory gene expression.

Sep 12, 2024 | nature.com | Stefan Günther |Mario Looso

AbstractThe innate immune response is triggered rapidly after injury and its spatiotemporal dynamics are critical for regeneration; however, many questions remain about its exact role. Here we show that MyD88, a key component of the innate immune response, controls not only the inflammatory but also the fibrotic response during zebrafish cardiac regeneration.

Jul 15, 2024 | nature.com | Stefan Günther |Nina Wettschureck

AbstractMultiple processes control quiescence of muscle stem cells (MuSCs), which is instrumental to guarantee long-term replenishment of the stem cell pool. Here, we describe that the G-proteins G12-G13 integrate signals from different G-protein-coupled receptors (GPCRs) to control MuSC quiescence via activation of RhoA.

Mar 21, 2024 | scholarsarchive.byu.edu | Stefan Günther

As early as 1995, James E. Young, referring to the “social effects of public memorial spaces” (p.20) in Germany, stated that “Holocaust memorial work in Germany today remains a tortured, self-reflective, even paralyzing preoccupation.” (p.21) He continues with a series of questions: “How does a state recite, much less commemorate, the litany of its misdeeds, making them part of its reason for being? Under what memorial aegis, whose rules, does a nation remember its own barbarity?