
Ting-Yu Lin
Articles
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Nov 22, 2024 |
mdpi.com | Ting-Yu Lin |Peng-Chieh Shen |Chu-Wen Tang |Fuk-Tan Tang
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Nov 22, 2024 |
onlinelibrary.wiley.com | Ting-Yu Lin |Po-Jui Chang |Chun-Yu Lo |Hsiao-Chi Chuang
CCR C-C motif chemokine receptor CRLF2 cytokine receptor-like factor 2 CRTH2 prostaglandin D2 receptor 2 FCER1A high affinity immunoglobulin epsilon receptor subunit alpha GINA global initiative for asthma ICS inhaled corticosteroid IL17RA interleukin-17 receptor A IL4RA interleukin-4 receptor α IL5RA interleukin-5 receptor α IL7R interleukin-7 receptor ITGA4 Integrin alpha-4 ITGB2 Integrin beta-2 LABA long-acting β agonist PAL persistent airflow limitation PCR polymerase chain reaction TGFB1...
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Jul 11, 2024 |
cell.com | Ting-Yu Lin |Leon Kleemann |Dominika Dobosz |Michał Rawski
Highlights•Single-particle cryo-EM structures reveal how human PUS3 recognizes tRNAs•Two distinct interfaces in PUS3 are key for tRNA binding and positioning•PUS1- but not PUS3-dependent Ψ sites are found in RNAs other than tRNAs•Patient-derived mutations link PUS3’s tRNA modification activity to human diseaseSummaryPseudouridine (Ψ), the isomer of uridine, is ubiquitously found in RNA, including tRNA, rRNA, and mRNA.
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Jun 28, 2024 |
mdpi.com | Long-Huei Lin |Ting-Yu Lin |Ke-Vin Chang |Wei-Ting Wu
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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May 14, 2024 |
nature.com | Marcin Jaciuk |Alexander Rau |Alexander Hammermeister |Michał Rawski |Paulina Indyka |Urszula Jankowska | +7 more
AbstracttRNA modifications affect ribosomal elongation speed and co-translational folding dynamics. The Elongator complex is responsible for introducing 5-carboxymethyl at wobble uridine bases (cm5U34) in eukaryotic tRNAs. However, the structure and function of human Elongator remain poorly understood. In this study, we present a series of cryo-EM structures of human ELP123 in complex with tRNA and cofactors at four different stages of the reaction.
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