Mingming Zhang

Sep 30, 2024 | mdpi.com | Yaqi Zhang |Feng Guo |Huan Zhang |Mingming Zhang

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.

Sep 29, 2024 | nature.com | Mingming Zhang |Pingqiang Cai

AbstractRegular physical activity is widely recognized for reducing the risk of various disorders, with skeletal muscles playing a key role by releasing biomolecules that benefit multiple organs and tissues. However, many individuals, particularly the elderly and those with clinical conditions, are unable to engage in physical exercise, necessitating alternative strategies to stimulate muscle cells to secrete beneficial biomolecules.

Jul 8, 2024 | blog.apnic.net | Mingming Zhang

Generated by AI. Domain names, vital for tasks like digital certificate authentication, face growing vulnerabilities in our evolving digital landscape. A key threat is hosting-based domain takeover, where adversaries exploit domains resolved to expired or unreferenced endpoints of public hosting platforms (for example, Content Delivery networks (CDNs), web hosting, and Operational Support Systems (OSS)).

Dec 5, 2023 | science.org | Yi Jiang |Huicong Liu |Leslie K. Ferrarelli |Yuejie Xu |Chengliang Zhu |Guifang Xu | +8 more

STAT3 palmitoylation initiates a positive feedback loop that promotes the malignancy of hepatocellular carcinoma cells in mice Yi Jiang https://orcid.org/0009-0000-6326-9611, Yuejie Xu, [...] , Chengliang Zhu https://orcid.org/0000-0002-8285-5795, Guifang Xu, [...] , Lei Xu, Zijian Rao, Lixing Zhou, Ping Jiang https://orcid.org/0000-0001-7204-0202, Sara Malik, [...] , Jingyuan Fang https://orcid.org/0000-0003-2282-0248, Hening Lin https://orcid.org/0000-0002-0255-2701 [email protected], and...

Nov 27, 2023 | nature.com | Mingming Zhang

AbstractLipid droplet (LD) accumulation is a notable feature of obesity-induced cardiomyopathy, while underlying mechanism remains poorly understood. Here we show that mice fed with high-fat diet (HFD) exhibited significantly increase in cardiac LD and RTN3 expression, accompanied by cardiac function impairment. Multiple loss- and gain-of function experiments indicate that RTN3 is critical to HFD-induced cardiac LD accumulation.