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Jan 22, 2025 | 
ccforum.biomedcentral.com | Freiburg im Breisgau |Faculté de Médecine |Nouvel Hôpital Civil
Simon A. Amacher and Caroline E. Gebhard planned and designed the study. Pimrapat Gebert performed the formal statistical analysis of the data provided by the Swiss Society of Intensive Care Medicine and the Federal Statistics Office. Simon A. Amacher, Pimrapat Gebert, and Caroline E. Gebhard interpreted the data. Caroline E. Gebhard and Simon A. Amacher wrote the inaugural draft of the manuscript. Simon A.
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Jan 15, 2025 | 
ccforum.biomedcentral.com | Clinical Applications
This study involved the analysis of prospective cohorts of adult patients with sepsis (n = 53) or septic shock (n = 63) and healthy controls (n = 50) from Zhongda Hospital, as well as pediatric septic patients (n = 88) or septic shock patients (n = 18) and healthy controls (n = 90) from the Children’s Hospital of Nanjing Medical University.
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Jan 14, 2025 | 
ccforum.biomedcentral.com | Fabio Silvio
ReferencesOddo M, Sandroni C, Citerio G, Miroz JP, Horn J, Rundgren M, et al. Quantitative versus standard pupillary light reflex for early prognostication in comatose cardiac arrest patients: an international prospective multicenter double-blinded study. Intensive Care Med. 2018;44(12):2102–11. Article PubMed PubMed Central Google Scholar Oddo M, Taccone FS, Petrosino M, Badenes R, Blandino-Ortiz A, Bouzat P, et al.
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Jan 12, 2025 | 
ccforum.biomedcentral.com | Anna Conway
An acute, unexpected ICU admission, especially in the presence of prognostic uncertainty, is a challenging, threatening, or aversive situation, a potential stressor [10]. This traumatic event which will affect each family member differently, depending on individual characteristics, type and characteristics of the event(s), developmental processes, the meaning attached to the trauma, and sociocultural factors [11].
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Jan 12, 2025 | 
ccforum.biomedcentral.com | Liver Diseases
This was a single-center, randomized, double-blind, placebo-controlled, phase 2 trial of inulin for the purpose of preventing gut pathogen colonization and infection in the ICU. Patients were randomized 1:1:1 to placebo, inulin 16 g/day, or inulin 32 g/day beginning on October 14, 2019. Prior to enrollment of the first patient, a data and safety monitoring board (DSMB) was appointed which had full access to the study data.
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Jan 8, 2025 | 
ccforum.biomedcentral.com | Related Diseases
Drs Bixin, Deng, Zhe, Zhao and conceptualized and designed the study, performed the analyses drafted the initial manuscript; Drs Tiechao Ruan, Ruixi Zhou, Chang'e Liu, Qiuping Li, Wenzhe Cheng, Jie Wang, Feng Wang, Haixiu Xie, Chenglong Li, Zhongtao Du, Wenting Lu coordinated data collection, collected data, and reviewed the manuscript; Drs Xiaohong Li, Junjie Ying, Tao Xiong, Xiaotong Hou, Xiaoyang Hong, and Dezhi Mu, revised the manuscript for important intellectual content; and all authors...
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Dec 17, 2024 | 
ccforum.biomedcentral.com | CHU Grenoble Alpes
Robust evidence has shown that crystalloid fluid expansion is beneficial to patients in circulatory shock in the first 6 h of their trauma. However, central clinical questions yet remain to be answered: Which clinical and/or paraclinical parameters should guide fluid initiation? In which context should crystalloid fluids be administered? In the prehospital setting? Which crystalloids should be used? Should they be continued upon hospital admission? How much fluids should be administered?
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Dec 4, 2024 | 
ccforum.biomedcentral.com | Andrew J E |Karen E. A |Albert Einstein College
Waveform monitoring is routinely performed for patients with impending or existing critical illness. Continuous vital sign monitoring typically involves recording of heart rate with single or multi-lead electrocardiogram (ECG), oxygen saturation with pulse oximetry, respiratory rate through chest impedance or capnography, and arterial blood pressure measured intermittently or continuously using an arterial catheter.
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Dec 2, 2024 | 
ccforum.biomedcentral.com | Khon Kaen
ReferencesDe Souza D, Machado F. Epidemiology of pediatric septic shock. J Pediatr Intensive Care. 2019;08(01):003–10. Article Google Scholar Watson RS, Carrol ED, Carter MJ, Kissoon N, Ranjit S, Schlapbach LJ. The burden and contemporary epidemiology of sepsis in children. Lancet Child Adolesc Health. 2024;8(9):670–81. Article PubMed Google Scholar Samransamruajkit R, Wong JJM, Smathakane C, Anantasit N, Sunkonkit K, Ong J, et al.
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Nov 25, 2024 | 
ccforum.biomedcentral.com | De Backer |Perioperative Care |Reggio Emilia
In the ATHOS 3 trial, 344 patients with vasodilatory shock (the vast majority being septic in etiology) were randomized to Ang II or placebo with continuation of background vasopressors. There was a significant increase in blood pressure. In about 70% of patients randomized to receive Ang II, the mean arterial pressure (MAP) rose to 75 mmHg or 10 mmHg above baseline, compared to only 23% in the placebo arm.