Begum Mathyk

Jun 10, 2024 | nature.com | Begum Mathyk |Alexander Quaas |Fathi Karouia |Nicolas Nelson |Ozlem Guzeloglu-Kayisli |Lauren Sanders | +12 more

AbstractAs the space industry grows exponentially and aspirations for space travel expand, we are entering a new era where we will very likely become an interplanetary species. Although reproduction is an essential human function and necessary for species survival, we have remarkably little knowledge regarding the impact of space travel on the female reproductive system.

Jun 10, 2024 | nature.com | JangKeun Kim |Braden T. Tierney |Eliah G. Overbey |Ezequiel Dantas |Jiwoon Park |Fei Wu | +16 more

AbstractSpaceflight induces an immune response in astronauts. To better characterize this effect, we generated single-cell, multi-ome, cell-free RNA (cfRNA), biochemical, and hematology data for the SpaceX Inspiration4 (I4) mission crew. We found that 18 cytokines/chemokines related to inflammation, aging, and muscle homeostasis changed after spaceflight.

Jun 10, 2024 | nature.com | Begum Mathyk |Marshall Tabetah |Rashid Karim |Victoria Zaksas |JangKeun Kim |Jiwoon Park | +6 more

AbstractOrganismal adaptations to spaceflight have been characterized at the molecular level in model organisms, including Drosophila and C. elegans. Here, we extend molecular work to energy metabolism and sex hormone signaling in mice and humans. We found spaceflight induced changes in insulin and estrogen signaling in rodents and humans.