Darko Barisic

Jan 15, 2025 | nature.com | Rui Yang |Renhe Luo |Martin Rivas |Martín A. Rivas |Darko Barisic |Alireza Karbalayghareh | +11 more

Correction to: Nature Communications https://doi.org/10.1038/s41467-024-53628-0, published online 01 November 2024In this article the affiliation ‘Department of Biochemistry & Molecular Biology; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA’ for Martin A. Rivas was missing. The original article has been corrected.

Nov 1, 2024 | nature.com | Rui Yang |Renhe Luo |Martin Rivas |Martín A. Rivas |Darko Barisic |Alireza Karbalayghareh | +11 more

AbstractIdentifying cell-type-specific 3D chromatin interactions between regulatory elements can help decipher gene regulation and interpret disease-associated non-coding variants. However, achieving this resolution with current 3D genomics technologies is often infeasible given limited input cell numbers. We therefore present ChromaFold, a deep learning model that predicts 3D contact maps, including regulatory interactions, from single-cell ATAC sequencing (scATAC-seq) data alone.

Jun 10, 2024 | nature.com | JangKeun Kim |Braden T. Tierney |Eliah G. Overbey |Ezequiel Dantas |Jiwoon Park |Fei Wu | +16 more

AbstractSpaceflight induces an immune response in astronauts. To better characterize this effect, we generated single-cell, multi-ome, cell-free RNA (cfRNA), biochemical, and hematology data for the SpaceX Inspiration4 (I4) mission crew. We found that 18 cytokines/chemokines related to inflammation, aging, and muscle homeostasis changed after spaceflight.

Mar 7, 2024 | cell.com | Darko Barisic |Christopher R Chin |Cem Meydan |Matt Teater

Delmas V. Stokes D.G. Perry R.P. A mammalian DNA-binding protein that contains a chromodomain and an SNF2/SWI2-like helicase domain. Proc. Natl. Acad. Sci. USA. 1993; 90: 2414-2418https://doi.org/10.1073/pnas.90.6.2414Shen X. Mizuguchi G. Hamiche A. Wu C. A chromatin remodelling complex involved in transcription and DNA processing. Nature. 2000; 406: 541-544https://doi.org/10.1038/35020123Tsukiyama T. Daniel C. Tamkun J. Wu C.