-
Nov 19, 2024 | 
nature.com | Simon Wiegrebe |Mathias Gorski |Klaus J. Stark |Christian Gieger |Johannes Schödel |Han Chen | +3 more
AbstractUnderstanding the genetics of kidney function decline, or trait change in general, is hampered by scarce longitudinal data for GWAS (longGWAS) and uncertainty about how to analyze such data. We use longitudinal UK Biobank data for creatinine-based estimated glomerular filtration rate from 348,275 individuals to search for genetic variants associated with eGFR-decline. This search was performed both among 595 variants previously associated with eGFR in cross-sectional GWAS and genome-wide.
-
Nov 12, 2024 | 
mdpi.com | Qiang Wu |Li Wang |Tianyi Wang |Han Chen
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
-
Sep 9, 2024 | 
aging-us.com | Su I Iao |Poorbita Kundu |Han Chen |James Carey
Research Perspective Volume 16, Issue 17 pp 12108—12122 1 Department of Statistics, University of California, Davis, CA 95616, USA 2 Department of Entomology, University of California, Davis, CA 95616, USA * Equal contribution https://doi.org/10.18632/aging.206106 How to Cite Cite this Article Select the format you require from the list below Click to copy this citation from the text box above or download the citation: Citation | Copyright: © 2024 Iao et al. This is an open access article...
-
Sep 9, 2024 | 
aging-us.com | Su I Iao |Poorbita Kundu |Han Chen |James Carey
Research Perspective Volume 16, Issue 17 pp 12108—12122 1 Department of Statistics, University of California, Davis, CA 95616, USA 2 Department of Entomology, University of California, Davis, CA 95616, USA * Equal contribution https://doi.org/10.18632/aging.206106 How to Cite Cite this Article Select the format you require from the list below Click to copy this citation from the text box above or download the citation: Citation | This is an open access article distributed under the terms of...
-
Sep 5, 2024 | 
foreignpolicy.com | Han Chen
A man taken into custody by border police agents during an operation against migrant smuggling waits on a truck next to a dog before being transferred near Santa Fe, located in the Darien province of Panama, on Aug. 7.
-
May 26, 2024 | 
rfa.org | Han Chen
Until two years ago, Peter Irwin, a Washington D.C.-based researcher, was able to access Chinese court data to track the number of Uyghurs being sentenced to prison. But amid the international outcry over Beijing’s oppressive policies in Xinjiang, the local court stopped publishing such data. Irwin was undeterred and pivoted his focus. It was a gradual process, he said, but he and his organization, the Uyghur Human Rights Project, or UHRP, took the time to adapt to the tighter data landscape.
-
May 17, 2024 | 
nature.com | Brian D. Piening |Maedeh Mohebnasab |Bo Xia |Jeffrey S. Stern |Weimin Zhang |Jacqueline I. Kim | +20 more
AbstractIn a previous study, heart xenografts from 10-gene-edited pigs transplanted into two human decedents did not show evidence of acute-onset cellular- or antibody-mediated rejection. Here, to better understand the detailed molecular landscape following xenotransplantation, we carried out bulk and single-cell transcriptomics, lipidomics, proteomics and metabolomics on blood samples obtained from the transplanted decedents every 6 h, as well as histological and transcriptomic tissue profiling.
-
Dec 25, 2023 | 
preprints.org | Li Yu |Wenyong Guo |Han Chen |Zhe Wu
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 23 December 2023 / Approved: 25 December 2023 / Online: 26 December 2023 (02:58:46 CET) Yu, L.; Guo, W.; Chen, H.T.; Wu, Z.; Cao, C.H.; Li, X.F.; Chen, S.Y. Fatigue Performance Analysis of an Underwater Vehicle Rud-der Mechanism Considering Arctic Low Temperatures. Preprints 2023, 2023121837.
-
Sep 1, 2023 | 
axios.com | Han Chen
The U.S. decision to impose visa restrictions on Chinese officials last week brought renewed attention to Beijing's yearslong efforts to tighten its grip on Tibet and other regions. Driving the news: The U.S. State Department last week announced visa curbs on Chinese officials involved in what it described as the "forcible assimilation" of Tibetan children in government-run boarding schools.
-
Aug 24, 2023 | 
dovepress.com | Han Chen |Dan Cao |Ning Han |Mingming Zhang
Back to Journals » Journal of Hepatocellular Carcinoma » Volume 10 Authors Chen H, Cao D , Han N, Zhang M, Jiang W, Wang X, Zeng Q, Tang H Received 24 August 2023 Accepted for publication 8 December 2023 Published 27 December 2023 Volume 2023:10 Pages 2337—2353 DOI https://doi.org/10.2147/JHC.S436926 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr David Gerber Han Chen,1,2 Dan Cao,1,2 Ning Han,1,2 Mingming...
