Hui Peng

Sep 30, 2024 | ascpt.onlinelibrary.wiley.com | Hui Wang |Maochang Liu |Xiaowen Wang |Hui Peng

CONFLICT OF INTEREST The authors declare no competing interests for this work. Supporting Information Filename Description cpt3448-sup-0001-Supinfo.docxWord 2007 document , 183.9 KB Data S1 References 1, & Idiopathic nephrotic syndrome in children. Lancet 392, 61–74 (2018). 2 et al. KDIGO 2021 Clinical Practice Guideline for the Management of Glomerular Diseases. Kidney Int. 100, S1–S276 (2021). 3 et al.

May 8, 2024 | nature.com | Hui Peng |He Wang |Weijia Kong |Jinyan Li

AbstractIdentification of differentially expressed proteins in a proteomics workflow typically encompasses five key steps: raw data quantification, expression matrix construction, matrix normalization, missing value imputation (MVI), and differential expression analysis. The plethora of options in each step makes it challenging to identify optimal workflows that maximize the identification of differentially expressed proteins.

Apr 16, 2024 | academic.oup.com | Sun Yat-sen |Lin Lin |Hui Peng

Chronic kidney disease (CKD) patients are at risk of developing end-stage kidney disease (ESKD), and cardio-cerebrovascular disease (CVD), and face increased mortality rates.

Mar 21, 2024 | nature.com | Jiabao Liu |Linhao Li |Holly Barrett |Jianxian Sun |William Navarre |Derek Wilson | +5 more

AbstractNumerous studies have demonstrated the correlation between human gut bacteria and host physiology, mediated primarily via nuclear receptors (NRs). Despite this body of work, the systematic identification and characterization of microbe-derived ligands that regulate NRs remain a considerable challenge. In this study, we discover a series of diindole molecules produced from commensal bacteria metabolites that act as specific agonists for the orphan constitutive androstane receptor (CAR).

Jan 12, 2024 | nature.com | Zhenzhong Yang |Fangyu Yue |Hui Peng |Rong Huang |Jie Jiang |Wei Tang | +5 more

AbstractAmong today’s nonvolatile memories, ferroelectric-based capacitors, tunnel junctions and field-effect transistors (FET) are already industrially integrated and/or intensively investigated to improve their performances. Concurrently, because of the tremendous development of artificial intelligence and big-data issues, there is an urgent need to realize high-density crossbar arrays, a prerequisite for the future of memories and emerging computing algorithms.