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1 month ago | 
onlinelibrary.wiley.com | Xu Zhang |Lu Zhou |Fengjiao Zhang |Hui Li
Aims The aim of this study was to investigate factors affecting psychosocial adaptation in intestinal stoma patients and to identify central symptoms that might guide future interventions through network analysis. Design A multicenter cross-sectional study. Methods All intestinal stoma patients were evaluated for psychosocial adaptation using the Ostomy Adjustment Inventory-20 (OAI-20).
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Nov 12, 2024 | 
dx.doi.org | Qingyuan Wu |Yuanyuan Zhong |Lu Zhou |Mengsi Zhu
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Nov 12, 2024 | 
pubs.acs.org | Qingyuan Wu |Yuanyuan Zhong |Lu Zhou |Mengsi Zhu
The catalyst support plays a pivotal role in regulating the geometric and electronic structure of active metal phases, thereby optimizing catalytic performance in terms of activity, selectivity, and stability. (1−10) Gamma alumina (γ-Al2O3) is a highly prevalent support material in catalysis, due to its high mechanical strength, high surface area, and relatively low production cost. (11−13) However, understanding the complex structure of γ-Al2O3 still presents a significant challenge.
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Oct 21, 2024 | 
hoganlovells.com | Jun S. Wei |Lu Zhou |Ying Tang
Insights and Analysis
A Practice Note setting out how to transfer equity interests of a limited liability company (LLC) incorporated in the People's Republic of China (PRC). It explains the statutory and typical contractual provisions that must be considered before transferring equity interests and the process and formalities of the transfer.
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Sep 26, 2024 | 
globaltimes.cn | Lu Zhou
A view of the Forbidden City along the Beijing Central Axis, a World Heritage Site. Photo: VCG Editor's Note:In today's world, where the futures of all countries are closely linked, development, security and civilization play important roles in promoting the modernization process of human society.
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Sep 17, 2024 | 
nature.com | Jiangdong Liu |Jinlei Qi |Peng Yin |Wei Liu |Ya Gao |Lu Zhou | +3 more
AbstractGlobal warming shifts daytime-only heatwaves to nighttime-only and day–night compound heatwaves. However, evidence on the cause-specific burdens of these heatwaves in a changing climate and ageing population is limited.
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Aug 1, 2024 | 
globaltimes.cn | Lu Zhou
The inscription of the Central Axis of Beijing on UNESCO's World Heritage List narrates a Chinese story of enduring civilization, blending the ancient with the modern. Illustration: Liu Xiangya/GTIt presents to the Chinese people a grand classroom for understanding the core values, history, and the spirit of traditional Chinese culture, and also provides new historical and cultural momentum for the sustainable development of the capital city.
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Aug 1, 2024 | 
onlinelibrary.wiley.com | Yuan-Hao Wen |Lu Zhou |Chen Lin |Yu-Xiu Lin
INTRODUCTION Apical periodontitis (AP), a destructive inflammatory disease caused by microorganisms, is characterized by persistent inflammatory response and alveolar bone resorption in the periapical area. In an epidemiological survey, AP was found to affect 52% of the global population, with a tooth-level prevalence of 5% (Tibúrcio-Machado et al., 2021). AP may not only lead to tooth loss but also affect general health by increasing the inflammatory burden (Jakovljevic et al., 2020).
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Jul 15, 2024 | 
nature.com | Gang Zhang |Hao LI |Bin Wang |Lu Zhou |Lun Fang |Zhongzhe Li | +2 more
Steroid-induced osteonecrosis of the femoral head (SONFH) is the predominant cause of non-traumatic osteonecrosis of the femoral head (ONFH). Impaired blood supply and reduced osteogenic activity of the femoral head are the key pathogenic mechanisms of SONFH. Fibroblast growth factor 23 (FGF23) levels are not only a biomarker for early vascular lesions caused by abnormal mineral metabolism, but can also act directly on the peripheral vascular system, leading to vascular pathology. The aim of this study was to observe the role of FGF23 on bone microarchitecture and vascular endothelium, and to investigate activation of pyroptosis in SONFH. Lipopolysaccharide (LPS) combined with methylprednisolone (MPS) was applied for SONFH mouse models, and adenovirus was used to increase or decrease the level of FGF23. Micro-CT and histopathological staining were used to observe the structure of the femoral head, and immunohistochemical staining was used to observe the vascular density. The cells were further cultured in vitro and placed in a hypoxic environment for 12 h to simulate the microenvironment of vascular injury during SONFH. The effect of FGF23 on osteogenic differentiation was evaluated using alkaline phosphatase staining, alizarin red S staining and expression of bone formation-related proteins. Matrigel tube formation assay in vitro and immunofluorescence were used to detect the ability of FGF23 to affect endothelial cell angiogenesis. Steroids activated the pyroptosis signaling pathway, promoted the secretion of inflammatory factors in SONFH models, led to vascular endothelial dysfunction and damaged the femoral head structure. In addition, FGF23 inhibited the HUVECs angiogenesis and BMSCs osteogenic differentiation. FGF23 silencing attenuated steroid-induced osteonecrosis of the femoral head by inhibiting the pyroptosis signaling pathway, and promoting osteogenic differentiation of BMSCs and angiogenesis of HUVECs in vitro.
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May 16, 2024 | 
ehp.niehs.nih.gov | Lu Zhou |Cong Liu |Jian Lei |Yixiang Zhu
: Environmental Health Perspectives Volume 132, Issue 5 CID: 057005 Introduction External causes of injury, including transportation-related injuries, self-harm, falls, and other injuries, are significant causes of death, particularly among young and middle-aged individuals.1–3 According to the global burden of disease (GBD) study,2 injuries caused about 249 million disability-adjusted life-years (DALYs) in 2019, with a high incidence and prevalence in the working-age population,4 leading to...
