Richa Batra

Oct 22, 2024 | alz-journals.onlinelibrary.wiley.com | Richa Batra |Jan Krumsiek |Xue Wang |Mariet Allen

1 BACKGROUND Tau protein hyperphosphorylation and its abnormal accumulation in the brain is a hallmark of several neurodegenerative diseases, including Alzheimer's disease (AD) and progressive supranuclear palsy (PSP).1 The major clinical symptom of AD is dementia, which predominantly impairs memory,2 whereas PSP is a Parkinsonian movement disorder.3 Despite both representing tauopathies, these diseases have several key differences: First, AD is a dual proteinopathy, displaying deposition of...

Sep 5, 2024 | nature.com | Annalise Schweickart |Richa Batra |Rima Kaddurah-Daouk |Anna Halama

AbstractRecent advances in high-throughput measurement technologies have enabled the analysis of molecular perturbations associated with disease phenotypes at the multi-omic level. Such perturbations can range in scale from fluctuations of individual molecules to entire biological pathways. Data-driven clustering algorithms have long been used to group interactions into interpretable functional modules; however, these modules are typically constrained to a fixed size or statistical cutoff.

Jun 11, 2024 | nature.com | JangKeun Kim |Eliah G. Overbey |Richa Batra |Annalise Schweickart |Deena Najjar |Cem Meydan | +6 more

AbstractAs spaceflight becomes more common with commercial crews, blood-based measures of crew health can guide both astronaut biomedicine and countermeasures. By profiling plasma proteins, metabolites, and extracellular vesicles/particles (EVPs) from the SpaceX Inspiration4 crew, we generated “spaceflight secretome profiles,” which showed significant differences in coagulation, oxidative stress, and brain-enriched proteins.

Sep 7, 2023 | biorxiv.org | Richa Batra |Rima Kaddurah-Daouk |Annalise Schweickart |Kelsey Chetnik

AbstractRecent advances in high-throughput measurement technologies have enabled the analysis of molecular perturbations associated with disease phenotypes at the multi-omic level. Such perturbations can range in scale from fluctuations of individual molecules to entire biological pathways. Data-driven clustering algorithms have long been used to group interactions into interpretable functional modules; however, these modules are typically constrained to a fixed size or statistical cutoff.

Apr 4, 2023 | ecampusnews.com | Richa Batra

So much has been asked of caregivers, especially those in the process of getting a college degree and balancing home and work responsibilities through the pandemic. According to the Institute for Women’s Policy Research, 4.8 million college students are simultaneously raising children. There also exists a great number of student caregivers who fall into the “”–those who are raising children and supporting their adult relatives simultaneously.