Ting Sun

Dec 1, 2024 | nature.com | Ting Sun

AbstractCancer has a high mortality rate across the globe, and tissue biopsy remains the gold standard for tumor diagnosis due to its high level of laboratory standardization, good consistency of results, relatively stable samples, and high accuracy of results. However, there are still many limitations and drawbacks in the application of tissue biopsy in tumor. The emergence of liquid biopsy provides new ideas for early diagnosis and prognosis of tumor.

Nov 9, 2024 | nature.com | Jun Tao |Wen Dai |Hang Liu |Juan Le |Ting Sun |Qian Yao | +4 more

Testosterone deficiency can cause abnormal lipid metabolism in men, leading to hyperlipidemia. We identified the testosterone-degrading bacterium Pseudomonas nitroreducens in the fecal samples of male patients with hyperlipidemia. Gastric administration of P. nitroreducens in mice led to testosterone deficiency and elevated blood lipid levels. Whole-genome sequencing of P. nitroreducens revealed the presence of 3/17β-hydroxysteroid dehydrogenase (3/17β-HSD), a gene responsible for testosterone degradation, which is also associated with hyperlipidemia. Microbiota analysis of fecal samples collected from 158 patients with hyperlipidemia and 151 controls revealed that the relative abundance of P. nitroreducens and 3/17β-HSD in the fecal samples of patients with hyperlipidemia was significantly higher than that in controls. These results suggest that P. nitroreducens and 3/17β-HSD may be related to the onset of testosterone deficiency-induced hyperlipidemia. Therefore, treatments targeted at eradicating testosterone-degrading bacteria are a potential future option for patients with testosterone-induced hyperlipidemia and should thus be studied further.

Oct 25, 2024 | mdpi.com | Weili Guo |Cheng Liu |Feng Xu |Ting Sun

1. IntroductionFrom 2014 to 2022, the European Maritime Safety Agency (EMSA) reported that there was a total of 21,173 maritime accidents, resulting in 6781 injuries and 604 lives lost [1]. Maritime accidents can result in catastrophic damages; thus, the maritime search and rescue (MSAR) operation is significant. In the International Aeronautical and Maritime Search and Rescue (IAMSAR) Manual, the maritime search is identified as one of the most dangerous and complex aspects of MSAR operations [2].

Aug 27, 2024 | opg.optica.org | Chenyu Wang |Zhihua Hu |Ting Sun

As the application of laser cleaning technology continues to expand, various fields have put forward higher requirements for the performance and quality of the operation, and at present, laser cleaning has problems such as low efficiency in handling repetitive tasks, and the system deployment and maintenance costs are high.

Aug 7, 2024 | pubs.acs.org | Bing Liu |Ting Sun |Yumeng Wang |Xiao-Yu Xia

1. IntroductionClick to copy section linkSection link copied!Mitochondria, which are crucial organelles within eukaryotic cells, play essential roles in cellular physiology including energy production, metabolism, and signaling pathways. (1) Additionally, they are intimately involved in various disease pathologies and therapeutic interventions.