Biotechniques: the International Journal of Life Science Methods

Biotechniques: the International Journal of Life Science Methods is a peer-reviewed journal that is available both in print and online, catering to researchers in molecular biology and biochemistry. The journal focuses on articles and reviews that discuss various techniques used in the field and is frequently referenced in other professional publications. It is included in prominent directories like Ulrich's and indexed in platforms such as Web of Science. The journal operates on an open access model and is funded through advertising. Published by Informa, it was founded in 1983 by Eaton Associates, which Informa later acquired in 2001.

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Articles

Integrating Organ-On-A-Chip Systems With Robotics And AI

1 week ago | biotechniques.com | Annie Coulson

The Center for Predictive in vitro Models (CPM) at Queen Mary University of London (QMUL; UK) brings together over 100 academic staff and post docs who specialize in developing and using organ-on-a-chip (OoC) technology and other types of predictive in vitro models. The center develops models for a broad range of tissues, organs and pathologies, while also conducting research into the underpinning bioengineering that is essential for the development of these models.
The latest innovations in organ-on-a-chip systems

1 week ago | biotechniques.com | Annie Coulson

The US FDA recently announced plans to phase out animal testing in the development of monoclonal antibodies and other drugs, replacing it with more effective, human-relevant methods, such as organ-on-a-chip (OoC) technology. OoCs are small – about the size of a USB memory stick – microfluidic devices lined with living human cells. Their ability to reproduce the physiological environment of human organs makes them ideal models for studying disease and developing drugs.
Novel drug-delivering aptamers target cancer stem cells with double punch

1 week ago | biotechniques.com | Annie Coulson

Drug-delivering aptamers that can precisely target leukemia stem cells with enhanced potency have been developed. Delivering anticancer drugs with specificity and potency to cancer stem cells is an increasing focus of leukemia therapeutic research and development, yet minimizing off-target toxicities remains a challenge.
Updates from the experts: bioimage analysis, genomics in space, imaging cytometry and epigenomics

2 weeks ago | biotechniques.com | Beatrice Bowlby

From AI and bioimage analysis to implementing genomic technologies in space research, the 2025 ABRF Annual Meeting (23-26 March 2025; Las Vegas, NV, USA) was packed with fascinating presentations, workshops and discussions. We spoke to four session speakers to learn about their favorite pieces of tech from the event, gain an insight into the discussions that arose in their sessions, and summarize their key takeaways from the Las Vegas meeting, What happens in Cores doesn’t stay in Cores.
The biotech bi-weekly: unveiling a next-generation PCR platform, accelerating drug discovery for glioblastoma and decoding cell communication

2 weeks ago | biotechniques.com | Beatrice Bowlby

In this edition of the biotech bi-weekly, read about the launch of a next-generation PCR kit, the development of a comprehensive functional genomics platform and the unveiling of a cryo-transmission electron microscope with enhanced automation capabilities. Plus, don’t miss the recent partnerships, publications and personnel appointments driving innovation in biotech.
Dark side of the genome: uncovering a critical protein network for maintaining healthy cells

2 weeks ago | biotechniques.com | Beatrice Bowlby

A key protein network that keeps cells safe from dangerous genes has been uncovered. A research team from La Jolla Institute for Immunology (CA, USA), The University of Queensland (Brisbane, Australia) and biomodal (Cambridge, UK) have uncovered how a critical protein network keeps cells safe from dangerous genes that have been noted in cancer, autoimmune disease and aging. This could help with future drug development and finding new avenues to treat diseases.
Take the plunge: cold-water acclimation affects cellular mechanisms

3 weeks ago | biotechniques.com | Beatrice Bowlby

The cellular changes induced by cold water plunges have been revealed. We’ve all heard about the potential health benefits of cold-water plunges, but what’s actually happening on a cellular level? Researchers in the Human and Environmental Physiology Research lab at the University of Ottawa (Canada) have investigated the effects of cold water acclimation on autophagic responses in young males.
Pressure-Sensing Protein Involved in Gut Motility Identified

3 weeks ago | biotechniques.com | Annie Coulson

A key pressure-sensing protein involved in intestinal movement and inflammation regulation has been identified. Researchers from Harvard Medical School (MA, USA) and the Icahn School of Medicine at Mount Sinai (NY, USA) have uncovered a key pressure-sensing protein involved in gut motility and immune balance, which could help develop precision-targeted treatments for intestinal disorders.
Fact or fiction: debunking scientific misinformation

3 weeks ago | biotechniques.com | Beatrice Bowlby

April Fools’ Day brings with it harmless pranks and little lies, for which the truth is usually swiftly revealed. However, the growing presence of misinformation – increasingly coming from individuals in positions of power – has meant that we’re faced with alarming headlines and baseless claims on a near daily basis, leaving it up to the reader to determine what’s fact and what’s fiction.
Novel approach for long-lasting contraceptives

3 weeks ago | biotechniques.com | Beatrice Bowlby

A new approach to drug formulation may enable the self-administration of drugs that last up to 2 years. With some drugs, like contraception, the requirement to take a pill daily can be a barrier for users. Now, researchers from the Massachusetts Institute of Technology (MIT; MA, USA) have devised a formulation that enables long-lasting medications to be self-administered. The approach could prove useful for contraceptives and other drugs that need to be administered over extended periods of time.