Diego Galeano

Oct 22, 2024 | nature.com | Diego Galeano |Victoria Zaksas |Stephen B. Baylin |Douglas C. Wallace |Frank J. Slack |Francisco J. Enguita | +1 more

AbstractMicroRNAs (miRNAs) have been implicated in human disorders, from cancers to infectious diseases. Targeting miRNAs or their target genes with small molecules offers opportunities to modulate dysregulated cellular processes linked to diseases. Yet, predicting small molecules associated with miRNAs remains challenging due to the small size of small molecule-miRNA datasets.

Oct 22, 2024 | flipboard.com | Diego Galeano |Jeffrey Haltom |Chaylen Andolino |Aliza Yousey |Victoria Zaksas |Saswati Das | +9 more

MicroRNAs (miRNAs) have been implicated in human disorders, from cancers to infectious diseases. Targeting miRNAs or their target genes with small …

Oct 15, 2024 | nature.com | JangKeun Kim |Francisco J. Enguita |Sylvain V Costes |Ryan Scott |Lauren Sanders |David Furman | +3 more

Correction to: Communications Biology https://doi.org/10.1038/s42003-024-06944-6, published online 05 October 2024In the Acknowledgement section, the L.I.G. was supported by the US Army Medical Research Command (award W81XWH2110402) was omitted. The original article has been corrected.

Oct 4, 2024 | nature.com | JangKeun Kim |Francisco J. Enguita |Sylvain V Costes |Ryan Scott |Lauren Sanders |David Furman | +3 more

AbstractIn the era of renewed space exploration, comprehending the effects of the space environment on human health, particularly for deep space missions, is crucial. While extensive research exists on the impacts of spaceflight, there is a gap regarding female reproductive risks. We hypothesize that space stressors could have enduring effects on female health, potentially increasing risks for future pregnancies upon return to Earth, particularly related to small-for-gestational-age (SGA) fetuses.

Jun 10, 2024 | nature.com | JangKeun Kim |Nídia S. Trovão |Keith Siew |Jiwoon Park |Eliah G. Overbey |Francisco J. Enguita | +12 more

AbstractOur previous research revealed a key microRNA signature that is associated with spaceflight that can be used as a biomarker and to develop countermeasure treatments to mitigate the damage caused by space radiation. Here, we expand on this work to determine the biological factors rescued by the countermeasure treatment.