Juliane H. Fröhner

Jul 14, 2024 | nature.com | Runye Shi |Shitong Xiang |Tianye Jia |Trevor Robbins |Jujiao Kang |Tobias Banaschewski | +21 more

AbstractAdolescents exhibit remarkable heterogeneity in the structural architecture of brain development. However, due to limited large-scale longitudinal neuroimaging studies, existing research has largely focused on population averages, and the neurobiological basis underlying individual heterogeneity remains poorly understood.

Jun 11, 2024 | fis.tu-dresden.de | IMAGEN Consortium |Juliane H. Fröhner |Michael N. Smolka

University of Amsterdam Universität Heidelberg King's College London (KCL) Trinity College Dublin Universität Mannheim Commissariat à l’énergie atomique et aux énergies alternatives (CEA) University of Vermont Physikalisch-Technische Bundesanstalt École normale supérieure Paris-Saclay Orsay Hospital Universitätsklinikum Schleswig-Holstein Campus Kiel Georg-August-Universität Göttingen Leibniz Institute for Neurobiology Fudan University Charité – Universitätsmedizin Berlin Berliner Institut...

Oct 19, 2023 | nature.com | Tobias Banaschewski |Gareth Barker |Sylvane Desrivières |Herta Flor |Penny Gowland |Andreas Heinz | +17 more

AbstractThe cerebral ventricles are recognized as windows into brain development and disease, yet their genetic architectures, underlying neural mechanisms and utility in maintaining brain health remain elusive. Here we aggregated genetic and neuroimaging data from 61,974 participants (age range, 9 to 98 years) in five cohorts to elucidate the genetic basis of ventricular morphology and examined their overlap with neuropsychiatric traits.

Sep 22, 2023 | nature.com | Feng Chen |Meiyun Wang |Xiaochu Zhang |Wen Qin |Feng Liu |Qiang Xu | +24 more

AbstractExposure to preadult environmental exposures may have long-lasting effects on mental health by affecting the maturation of the brain and personality, two traits that interact throughout the developmental process. However, environment-brain-personality covariation patterns and their mediation relationships remain unclear.

Aug 21, 2023 | nature.com | Seyed Mostafa Kia |Sebastian Siehl |Sylvane Desrivières |Herta Flor |Penny Gowland |Andreas Heinz | +13 more

AbstractEnvironmental adversities constitute potent risk factors for psychiatric disorders. Evidence suggests the brain adapts to adversity, possibly in an adversity-type and region-specific manner. However, the long-term effects of adversity on brain structure and the association of individual neurobiological heterogeneity with behavior have yet to be elucidated.