
Articles
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Sep 10, 2024 |
dx.doi.org | Stephanie Le |Prachi Gupta |Ranit Dutta |Jithu Krishna
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Aug 22, 2024 |
nature.com | Selene Lickfett |Agnieszka Rybak-Wolf |Carmen Menacho |Stephanie Le |Tancredi Massimo Pentimalli |Daniel Oehler | +14 more
AbstractExpansion of the glutamine tract (poly-Q) in the protein huntingtin (HTT) causes the neurodegenerative disorder Huntington’s disease (HD). Emerging evidence suggests that mutant HTT (mHTT) disrupts brain development. To gain mechanistic insights into the neurodevelopmental impact of human mHTT, we engineered male induced pluripotent stem cells to introduce a biallelic or monoallelic mutant 70Q expansion or to remove the poly-Q tract of HTT.
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May 13, 2024 |
agsjournals.onlinelibrary.wiley.com | Jeffrey Levine |Emily Samuels |Stephanie Le |Ruth Spinner
RESEARCH LETTER Pressure injuries and wound care: A lost geriatric syndrome Jeffrey M. Levine MD, AGSF, Corresponding Author Jeffrey M. Levine MD, AGSF Icahn School of Medicine at Mount Sinai, New York, New York, USA Correspondence Jeffrey M. Levine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
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Mar 22, 2024 |
cell.com | Stephanie Le |Heinrich Heine |Carmen Menacho |Alessandro Prigione
AbstractIn a recent study, Rylaarsdam and colleagues revealed that mutant PACS1 gene, which causes a rare neurodevelopmental syndrome, affects the firing ability of human neurons without dysregulating the cellular architecture of brain organoids. These findings suggest aberrant neuronal electrophysiology as a possible interventional target for pediatric diseases impairing brain development.
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Dec 5, 2023 |
medium.com | Stephanie Le
Google Cloud Next’23 (GCN’23), a gathering of tech enthusiasts, innovators, and leaders from around the globe, was such a mind-expanding experience to me. As one of the 180 Google Cloud Student Innovators sponsored to attend the conference at the Moscone Center in the Bay Area, I was thrilled to be among the first to test the latest AI integration updates and features in the world of Google Cloud and also connect with a global community of like-minded individuals.
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