Zhigang Li

Oct 29, 2024 | science.org | Vincent Rondeau |Zhigang Li |Amy Baek |Xiaxi Dong

Editor’s summaryIn contrast to the neonatal mammalian heart, in which cardiomyocyte proliferation can enable complete repair, cardiomyocytes in the adult mammalian heart must be induced to reenter the cell cycle to achieve regeneration. Increases in purine availability are required to support enhanced DNA and RNA synthesis during proliferation, leading Li et al. to investigate how cardiac regeneration is affected by Adssl1, a critical enzyme in de novo purine synthesis.

Oct 29, 2024 | science.org | Vincent Rondeau |Zhigang Li |Amy Baek

AbstractA neuropeptide-receptor pair promotes the differentiation of TH1 cells and enhances their response to viral infection. SIGN UP FOR THE SCIENCEADVISER NEWSLETTER The latest news, commentary, and research, free to your inbox daily Helper T cells, such as TH1, TH2, TH17, and Treg cells, are important in adaptive immune responses to infectious diseases, antitumor immunity, and autoimmunity.

Oct 29, 2024 | science.org | Vincent Rondeau |Zhigang Li |Amy Baek |Maria Kalogeraki

Editor’s summaryTruncations of the chemokine receptor CXCR4 prevent its internalization and cause WHIM syndrome, an inherited immunodeficiency characterized by increased numbers of myeloid cells in the bone marrow. In a mouse model of WHIM syndrome, Rondeau et al. found that a subset of multipotent progenitor cells that normally adopt a lymphoid fate were reprogrammed to instead adopt a myeloid fate.

Aug 20, 2024 | mdpi.com | Jie Yang |Zhigang Li

1. IntroductionIn the context of the rapid development of urbanization in China, the improvement of ecological welfare performance (EWP) in the Yangtze River Economic Belt (YREB), as an important economic growth region, has become the key to achieve sustainable development [1].

Mar 28, 2024 | onlinelibrary.wiley.com | Qianqian Liu |Automation Hefei |Zhigang Li |Yigang He

CONFLICT OF INTEREST The authors declare no conflict of interest. REFERENCES 1, , , , . Adaptive combination of Volterra kernels and its application to nonlinear acoustic echo cancellation. IEEE Trans Audio Speech Lang Process. 2011; 19(1): 97-110. doi:10.1109/TASL.2010.2045185 2, . Second-order Volterra filtering and its application to nonlinear system identification. IEEE Trans Acoust Speech Signal Process. 1985; 33(6): 1445-1455. 3, , .