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2 months ago | 
nature.com | Qingyang Li |Miao Cao |Dan Stein |Barbara Sahakian |Tianye Jia |Christelle Langley | +22 more
AbstractLaboratory studies show brain maturation involves synaptic pruning and cognitive development. Human studies suggest links between early cognitive performance and later mental health, but inconsistencies remain. It is unclear if specific brain regions mediate this relationship, and the molecular underpinnings are not well understood.
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Jan 9, 2025 | 
nature.com | Xinyang Yu |Zuo Zhang |Moritz Herle |Tobias Banaschewski |Gareth Barker |Herta Flor | +16 more
AbstractUnhealthy eating, a risk factor for eating disorders (EDs) and obesity, often coexists with emotional and behavioral problems; however, the underlying neurobiological mechanisms are poorly understood. Analyzing data from the longitudinal IMAGEN adolescent cohort, we investigated associations between eating behaviors, genetic predispositions for high body mass index (BMI) using polygenic scores (PGSs), and trajectories (ages 14–23 years) of ED-related psychopathology and brain maturation.
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Sep 15, 2024 | 
nature.com | Gunter Schumann |Amy Bernard |Sylvane Desrivières |Jianfeng Feng |Peng Gong |Andreas Heinz | +3 more
Announced in this Comment and in collaboration with Nature Mental Health is the convening of the Earth Brain Health Commission, addressing innovative and multidisciplinary approaches to mitigating environment-related mental health harms and promoting wellbeing.
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Jul 14, 2024 | 
nature.com | Runye Shi |Shitong Xiang |Tianye Jia |Trevor Robbins |Jujiao Kang |Tobias Banaschewski | +21 more
AbstractAdolescents exhibit remarkable heterogeneity in the structural architecture of brain development. However, due to limited large-scale longitudinal neuroimaging studies, existing research has largely focused on population averages, and the neurobiological basis underlying individual heterogeneity remains poorly understood.
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Nov 5, 2023 | 
nature.com | Gunter Schumann
This Comment proposes to increase knowledge of the effects of urbanicity on brain and mental health by linking existing human spatial data with macroenvironmental and regional socioeconomic data. It introduces hypothesis-free models to capture the data and model life in the city and suggests refinements for future studies into conditions that will soon affect the majority of the earth’s population. We are all exposed to a complex environment that affects our health.
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Oct 19, 2023 | 
nature.com | Tobias Banaschewski |Gareth Barker |Sylvane Desrivières |Herta Flor |Penny Gowland |Andreas Heinz | +17 more
AbstractThe cerebral ventricles are recognized as windows into brain development and disease, yet their genetic architectures, underlying neural mechanisms and utility in maintaining brain health remain elusive. Here we aggregated genetic and neuroimaging data from 61,974 participants (age range, 9 to 98 years) in five cohorts to elucidate the genetic basis of ventricular morphology and examined their overlap with neuropsychiatric traits.
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Aug 23, 2023 | 
jamanetwork.com | Gunter Schumann |Clinical Neuroscience |Charité Universitätsmedizin Berlin |Tobias Banaschewski
Addressing Global Environmental Challenges to Mental Health Using Population Neuroscience: A Review
Abstract
Importance
Climate change, pollution, urbanization, socioeconomic inequality, and psychosocial effects of the COVID-19 pandemic have caused massive changes in environmental conditions that affect brain health during the life span, both on a population level as well as on the level of the individual.
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Aug 21, 2023 | 
nature.com | Seyed Mostafa Kia |Sebastian Siehl |Sylvane Desrivières |Herta Flor |Penny Gowland |Andreas Heinz | +13 more
AbstractEnvironmental adversities constitute potent risk factors for psychiatric disorders. Evidence suggests the brain adapts to adversity, possibly in an adversity-type and region-specific manner. However, the long-term effects of adversity on brain structure and the association of individual neurobiological heterogeneity with behavior have yet to be elucidated.
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Aug 15, 2023 | 
nature.com | Shitong Xiang |Tianye Jia |Tobias Banaschewski |Gareth Barker |Christian Büchel |Sylvane Desrivières | +15 more
AbstractSmoking of cigarettes among young adolescents is a pressing public health issue. However, the neural mechanisms underlying smoking initiation and sustenance during adolescence, especially the potential causal interactions between altered brain development and smoking behaviour, remain elusive.
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Aug 9, 2023 | 
nature.com | Shitong Xiang |Xuerui Peng |Tobias Banaschewski |Gareth Barker |Christian Büchel |Herta Flor | +17 more
Correction to: Nature Medicine https://doi.org/10.1038/s41591-023-02317-4. Published online 24 April 2023. In the version of this article initially published, the STRATIFY data also included cohort data from the ESTRA consortium, though this was not acknowledged in the author list and the section in Methods on the Stratify dataset. The Methods are now updated, and the author list is amended to combine the STRATIFY and ESTRA consortium names and to include the following authors: Marina Bobou, M.
