-
2 months ago | 
nature.com | Qingyang Li |Miao Cao |Dan Stein |Barbara Sahakian |Tianye Jia |Christelle Langley | +22 more
AbstractLaboratory studies show brain maturation involves synaptic pruning and cognitive development. Human studies suggest links between early cognitive performance and later mental health, but inconsistencies remain. It is unclear if specific brain regions mediate this relationship, and the molecular underpinnings are not well understood.
-
Jan 14, 2025 | 
nature.com | Edmund T. Rolls |Jianfeng Feng
AbstractTo understand the neural mechanism of autism spectrum disorder (ASD) and developmental delay/intellectual disability (DD/ID) that can be associated with ASD, it is important to investigate individuals at an early stage with brain, behavioural and also genetic measures, but such research is still lacking.
-
Jan 8, 2025 | 
thehindu.com | Barbara Sahakian |Christelle Langley |Chun Shen |Jianfeng Feng
Human beings are inherently social. We thrive on connection, communication and shared experiences, which help shape our identities and foster a sense of belonging. Yet, in an increasingly digital and fast-paced world, feelings of loneliness and social isolation have become alarmingly common. The World Health Organization (WHO) has stated that these feelings are widespread. About 25% of older people and 5%-15% of adolescents feel lonely.
-
Nov 18, 2024 | 
nature.com | Yu Guo |Linbo Wang |Jujiao Kang |Qiang Dong |Jianfeng Feng |Wei Cheng
AbstractPathophysiological evolutions in early-stage Alzheimer’s disease (AD) are not well understood. We used data of 2923 Olink plasma proteins from 51,296 non-demented middle-aged adults. During a follow-up of 15 years, 689 incident AD cases occurred. Cox-proportional hazard models were applied to identify AD-associated proteins in different time intervals. Through linking to protein categories, changing sequences of protein z-scores can reflect pathophysiological evolutions.
-
Sep 15, 2024 | 
nature.com | Gunter Schumann |Amy Bernard |Sylvane Desrivières |Jianfeng Feng |Peng Gong |Andreas Heinz | +3 more
Announced in this Comment and in collaboration with Nature Mental Health is the convening of the Earth Brain Health Commission, addressing innovative and multidisciplinary approaches to mitigating environment-related mental health harms and promoting wellbeing.
-
Jul 16, 2024 | 
nature.com | Jianfeng Feng
-
Jul 15, 2024 | 
nature.com | Yue-Ting Deng |Jujiao Kang |Ying Zhu |Qiang Dong |Jianfeng Feng |Wei Cheng
AbstractThe genetic contribution of protein-coding variants to immune-mediated diseases (IMDs) remains underexplored. Through whole exome sequencing of 40 IMDs in 350,770 UK Biobank participants, we identified 162 unique genes in 35 IMDs, among which 124 were novel genes. Several genes, including FLG which is associated with atopic dermatitis and asthma, showed converging evidence from both rare and common variants.
-
Jul 14, 2024 | 
nature.com | Runye Shi |Shitong Xiang |Tianye Jia |Trevor Robbins |Jujiao Kang |Tobias Banaschewski | +21 more
AbstractAdolescents exhibit remarkable heterogeneity in the structural architecture of brain development. However, due to limited large-scale longitudinal neuroimaging studies, existing research has largely focused on population averages, and the neurobiological basis underlying individual heterogeneity remains poorly understood.
-
May 6, 2024 | 
www1.folha.uol.com.br | Barbara Sahakian |Christelle Langley |Jianfeng Feng |Wei Cheng
Da crocância crocante dos vegetais frescos à indulgência cremosa das sobremesas decadentes, todos nós temos preferências alimentares diferentes. Nossos paladares se desenvolvem de forma única, moldados pela genética, cultura e experiências pessoais.
As preferências alimentares desempenham um papel importante na formação de nossos hábitos alimentares. Alimentos altamente palatáveis, ricos em açúcares, gorduras e sais, geralmente atraem o paladar das pessoas e proporcionam satisfação imediata.
-
Apr 12, 2024 | 
scroll.in | Barbara Sahakian |Christelle Langley |Jianfeng Feng |Wei Cheng
From the crispy crunch of fresh veggies to the creamy indulgence of decadent desserts, we all have different food preferences. Our palates develop uniquely, shaped by genetics, culture and personal experiences. Food preferences play a significant role in shaping our dietary habits. Highly palatable foods rich in sugars, fats and salts often appeal to people’s tastebuds and provide immediate satisfaction.
