Paul Clarke
Group Sport Editor at National World Publishing
Group Sport Editor @NatWorldPub Previously sports content editor and reporter at Reach PLC.
Articles
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Oct 4, 2024 |
pubs.rsc.org | William Paul Unsworth |Paul Clarke |Saikiran Ravi |Christopher J Maddocks
Asymmetric ‘Clip-Cycle’ Synthesis of 3-Spiropiperidines 3-Spiropiperidines can be synthesized in up to 87% yield and 96:4 er using a two step ‘Clip-Cycle’ approach. The ‘Clip’ stage of this method is based on efficient and highly E-selective cross metathesis of N-Cbz-protected 1-amino-hex-5-enes with a thioacrylate. This is followed by the ‘Cycle’ step, in which an intramolecular asymmetric aza-Michael cyclization is promoted by a chiral phosphoric acid catalyst.
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Jul 14, 2023 |
sdcexec.com | Paul Clarke
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May 24, 2023 |
nature.com | Paul Clarke
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May 4, 2023 |
northwestend.com | Paul Clarke
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Apr 20, 2023 |
northwestend.com | Paul Clarke
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