Cancer Cell

Cell Press is responsible for publishing more than 50 scientific journals that cover a wide range of fields, including life, physical, earth, and health sciences. This initiative operates both independently and in collaboration with various scientific societies. Our journey started more than 45 years ago with the launch of the journal Cell, driven by a dedication to sharing groundbreaking biology research. Today, we continue to uphold our high editorial standards, embrace innovation, and expand our visibility and influence. Our goal is to promote and disseminate science that motivates and inspires exploration across all scientific domains.

International

English

Journal

Outlet metrics

Domain Authority

Ranking

Global

#16327

United States

#10310

Science and Education/Biology

#13

Traffic sources

Monthly visitors

Articles

The recency and geographical origins of the bat viruses ancestral to SARS-CoV and SARS-CoV-2

1 week ago | cell.com | Jonathan Pekar |Spyros Lytras |Mahan Ghafari |Andrew Magee |Edyth Parker |Yu Wang | +13 more

Keywords molecular epidemiology sarbecoviruses virus evolution phylogeography Introduction Horseshoe bats (Rhinolophus spp.) are the main hosts of the Sarbecovirus subgenus1 (genus Betacoronavirus, family Coronaviridae) and, likely via virus transmission through transient intermediate species, were the source of SARS-CoV (referred to hereafter as SARS-CoV-1, now extinct) and SARS-CoV-2.2,3,4 Since the first emergence of SARS-CoV-1 in Guangzhou, Guangdong Province, in 2002 and SARS-CoV-2...
Pooled tagging and hydrophobic targeting of endogenous proteins for unbiased mapping of unfolded protein responses

2 weeks ago | cell.com | Stephanie E Sansbury |Yevgeniy V. Serebrenik |Tomer Lapidot |David SMith |David Smith |George M. Burslem | +1 more

Keywordspooled taggingproteostasisin situ sequencingprotein misfoldingprotein localizationhydrophobic targetingIntroductionLarge-scale multiplexed imaging and gene perturbation technologies have transformed mammalian cell biology but are predominantly limited to nucleic acids. This is due to the ease of generating specific targeting reagents via sequence complementarity, which does not extend to the proteins.
Immunothrombolytic monocyte-neutrophil axes dominate the single-cell landscape of human thrombosis and correlate with thrombus resolution

3 weeks ago | cell.com | Kami Pekayvaz |Badr Kilani |Markus Joppich |Luke Eivers |Sophia Brambs |Viktoria Knottenberg | +31 more

Keywords immunothrombosis thrombosis immune landscape neutrophils monocytes innate immunity single-cell multi-omics immunothrombolysis thrombus resolution immunothrombotic dysregulation thromboinflammation stroke immune-cell plasticity organ ischemia Introduction Thrombosis and thromboembolism are a major global cause of morbidity and mortality by leading to myocardial infarction, stroke, and venous thromboembolism.1,2 Simultaneously, anti-thrombotic therapies carry a relevant risk of...
Nitric oxide controls stomatal development and stress responses by inhibiting MPK6 phosphorylation via S-nitrosylation in Arabidopsis

3 weeks ago | cell.com | Danfeng Wang |Hongyan Guo |Xinru Gong |Lichao Chen |Huifang Lin |Shiping Wang | +7 more

Keywordsstomatanitric oxideS-nitrosylationMAPKMPK6SPCHstress responsesABAGet full text accessLog in, subscribe or purchase for full access. References1. Casson, S.A. ∙ Hetherington, A.M.Environmental regulation of stomatal developmentCurr. Opin. Plant Biol. 2010; 13:90-952. Ye, W. ∙ Munemasa, S. ∙ Shinya, T. ... Stomatal immunity against fungal invasion comprises not only chitin-induced stomatal closure but also chitosan-induced guard cell deathProc. Natl. Acad. Sci. USA. 2020; 117:20932-209423. Zhang, J.
Alpha-synuclein mutations mislocalize cytoplasmic p300 compromising autophagy, which is rescued by ACLY inhibition

3 weeks ago | cell.com | Sung Min Son |Farah Siddiqi |Ana Lopez |Ana López |Rizwan Ansari |Sylwia D. Tyrkalska | +4 more

ArticleOnline nowOpen access 1Cambridge Institute for Medical Research (CIMR), University of Cambridge, Cambridge, UK 2UK Dementia Research Institute, Cambridge Institute for Medical Research (CIMR), University of Cambridge, Cambridge, UK 3Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK 4UK Dementia Research Institute, Department of Clinical Neurosciences, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK 5Centre for...
Comparative transcriptomic insights into the evolution of vertebrate photoreceptor types

4 weeks ago | cell.com | Dario Tommasini |Takeshi Yoshimatsu |Teresa Puthussery |Tom Baden |Karthik Shekhar

1Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA 94720, USA 2Department of Ophthalmology and Visual Sciences, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA 3Vision Sciences Graduate Group, University of California, Berkeley, Berkeley, CA 94720, USA 4Herbert Wertheim School of Optometry and Vision Science, University of California, Berkeley, Berkeley, CA 94720, USA 5Center for Sensory Neuroscience and Computation, Sussex...
Now you see me, now you don’t: What and how viral RNAs are detected by cytoplasmic pattern-recognition receptors

4 weeks ago | cell.com | Raul Andino |Daniel Darling

Get full text accessLog in, subscribe or purchase for full access. References1. Genoyer, E. ∙ Wilson, J. ∙ Ames, J.M. ... Exposure of negative-sense viral RNA in the cytoplasm initiates innate immunity to West Nile virusMol. Cell. 2025; 85:1147-1161.e92. Chow, K.T. ∙ Gale, Jr., M. ∙ Loo, Y.-M. RIG-I and Other RNA Sensors in Antiviral ImmunityAnnu. Rev. Immunol. 2018; 36:667-6943. Yoneyama, M. ∙ Kikuchi, M. ∙ Natsukawa, T. ...
PP1/PNUTS phosphatase binds the restrictor complex and stimulates RNA Pol II transcription termination

1 month ago | cell.com | Benjamin Erickson |Roman O Fedoryshchak |Nova Fong |Ryan Sheridan |Keira larson |Anthony J. Saviola | +4 more

KeywordsPol II CTD Ser5 phosphorylationCTD dephosphorylationPP1 phosphataserestrictorWDR82ZC3H4transcription terminationtranscription elongationResearch topic(s)CP: Molecular biologyIntroductionA large fraction of promoters in multicellular organisms have bidirectional character and give rise to both sense and divergent antisense transcription, which must eventually terminate to prevent interference with neighboring genes and collisions with replication forks.
Precision oncology and genetic ancestry: The science behind population-based cancer disparities

1 month ago | cell.com | Melissa Davis |Rachel Martini

Main textCurrent precision medicine approaches often fail to account for genetic ancestry, leading to disparities in diagnosis, treatment response, and outcomes. The performance and interpretation of precision oncology tools, including next-generation sequencing panels, liquid biopsies, and other genomic assays, can vary significantly across patient populations with diverse genetic ancestries.
Bridging the gap: The future of cancer research and clinical oncology in Cancer Cell

1 month ago | cell.com | Steve Mao

Main textOver the past five years, Cancer Cell has undergone a transformative evolution, reflecting the increasing multidisciplinary and integrative nature of cancer research. As editor-in-chief, it has been both a privilege and a profound responsibility to guide this journal through a period of significant change and growth, ensuring that it remains at the forefront of cancer research while adapting to the evolving needs of the scientific community.