Respiratory Research

Respiratory Research is a prominent journal that focuses on publishing top-notch clinical and fundamental research, along with review articles and commentaries related to respiratory medicine and associated diseases. As the leading fully open access journal in this area, it serves as a vital resource for pulmonologists, allergists, immunologists, and other medical professionals, researchers, healthcare providers, and students around the globe. The journal ensures that articles reach a wide audience, sparking international conversations and enhancing visibility. Key topics explored in the journal include asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, genetic factors, infectious diseases, interstitial lung diseases, lung development, lung tumors, as well as the impact of occupational and environmental factors. It also covers pulmonary circulation, pharmacology and therapeutics related to the lungs, respiratory immunology, respiratory physiology, and sleep-related breathing issues.

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Articles

A novel technique of cryodenervation for murine vagus nerve: implications for acute lung inflammation - Respiratory Research

Jan 13, 2025 | respiratory-research.biomedcentral.com | Di Wu |Jing Gao |Kun Wang |Wujian Xu |Feilong Wang |Zhixian Jin | +4 more

Instead of expensive and giant cryoablation equipment used in clinic, the instruments required for VSCD are commonly available in general laboratories, mainly including liquid nitrogen tank, liquid nitrogen pen, stereomicroscope, microforceps, 75% alcohol, operating board, ophthalmic curved scissors, hemostat, forceps, and timer (Fig. 1A).
Airway pressures generated by high flow nasal cannula in patients with acute hypoxemic respiratory failure: a computational study - Respiratory Research

Jan 8, 2025 | respiratory-research.biomedcentral.com | Reggio Emilia |Galway Hospitals

No patients were involved in the study, all results are based on modelling of data from previously published studies. To investigate the relationship between functional lung volume and airway pressures produced by HFNC, we adapted a multi-compartmental computational simulator, previously employed to simulate patients with different conditions, such as COVID-19 [15], chronic obstructive pulmonary disease (COPD) [16], ARDS [17, 18] and AHRF [19].
Dynamic EIT technology for real-time non-invasive monitoring of acute pulmonary embolism: a porcine model experiment - Respiratory Research

Jan 8, 2025 | respiratory-research.biomedcentral.com | Biomedical Engineering

The experimental animals were 12 female anaesthetised domestic pigs. Their mean weight and mean chest circumference of the subjects were 20.75 ± 2.56 kg and 57.67 ± 3.26 cm, respectively, and they were 2.5-3.0 months old. The study was approved by the Animal Welfare and Ethics Committee of the Air Force Medical University.
The different response of PM2.5 stimulated nasal epithelial spheroids in control, asthma and COPD groups - Respiratory Research

Jan 8, 2025 | respiratory-research.biomedcentral.com | Pulmonary Diseases

ReferencesBurnett R, Chen H, Szyszkowicz M, Fann N, Hubbell B, Pope CA, et al. Global estimates of mortality associated with long-term exposure to outdoor fine particulate matter. Proc Natl Acad Sci U S A. 2018;115:9592–7. Article CAS PubMed PubMed Central Google Scholar Juginović A, Vuković M, Aranza I, Biloš V. Health impacts of air pollution exposure from 1990 to 2019 in 43 European countries. Sci Rep. 2021;11:22516.
Interaction study of the effects of environmental exposure and gene polymorphisms of inflammatory and immune-active factors on chronic obstructive pulmonary disease | Respiratory Research | Full Text

Jan 8, 2025 | respiratory-research.biomedcentral.com | Jiangsu College

In our previous study [3], we compared the characteristics of 471 cases and 485 controls with respect to the main demographic characteristics, disease history, environmental exposure, lifestyle, dietary habits and disease history. Statistical differences were found in age, income, education, BMI, smoking, indoor fuel use (no fuel/natural gas/electricity vs.
Identification of progressive pulmonary fibrosis: consensus findings from a modified Delphi study - Respiratory Research

Dec 31, 2024 | respiratory-research.biomedcentral.com | Athol U Wells |Ayodeji Adegunsoye |Vincent Cottin |Sonye Danoff |Anand Devaraj |Kevin Flaherty | +7 more

Surveys were completed between March 2022 and July 2023. The international guideline on the definition of PPF [1] was published between distribution of the first and second rounds of the survey. The first survey was sent to 405 physicians in 32 countries and completed by 207, of whom 131 completed the second round and 94 completed the third round. The clinical experience of the respondents is summarised in Table S1 in Additional file 1.
Changes in muscle-to-fat ratio are associated with lung function decline and airflow obstruction in the general population - Respiratory Research

Dec 26, 2024 | respiratory-research.biomedcentral.com | Eunwoo Kim |Ah Young Leem |Ji Ye Jung |Young Kim |Youngmok Park

This study used data from the Korean Genome and Epidemiology Study (KoGES), a prospective community-based cohort. The cohort consists of 10,030 men and women aged 40–69 years old, living in Ansan (an urban community) and Anseong (a rural community). A follow-up study has been conducted there biannually from 2001 [16]. Quality-controlled spirometry results were first obtained during the 2nd follow-up.
CTSS contributes to airway neutrophilic inflammation in mixed granulocytic asthma - Respiratory Research

Dec 24, 2024 | respiratory-research.biomedcentral.com | Haixiong Tang |Changyun Yang |Lin Fu |Xiaolong Ji |Zemin Chen |Hailing Zhang | +8 more

Tang H, Li J and Yao L designed this study. Li J and Chen X supervised the whole study. Tang H, Yang CY and Fu L performed most of the experiments. Tang H and Ji XL analyzed the results and wrote the manuscript. Chen Z helped with the data analysis. Gan S and Zhang WJ helped with the in vitro experiments. Zhang H and Zhang pingAn helped with the animal experiments. Li S helped to collect the clinical data. Li J, Chen X and Yao L revised the manuscript.
A worldwide assessment of the mechanical ventilation in patients with acute exacerbations of chronic obstructive pulmonary disease. Analysis of the VENTILAGROUP over time. A retrospective, multicenter study | Respiratory Research | Full Text

Dec 18, 2024 | respiratory-research.biomedcentral.com | Óscar Peñuelas |Laura del Campo-Albendea |Alfonso Muriel |Arnaud W Thille |Bin Du |Bruno Pinheiro | +9 more

The study design was a retrospective analysis of the observational study performed by the International Study Group on Mechanical Ventilation [VENTILAGROUP] [15].
Development and validation of a Prediction Model for Chronic Thromboembolic Pulmonary Disease - Respiratory Research

Dec 18, 2024 | respiratory-research.biomedcentral.com | Guixiang Liu |Jing Wen |Chunyi Lv |Mingjie Liu |Nannan Zhang |Xuehua Li | +5 more

Consecutive patients with APE confirmed between January 2020 and September 2023, at 7 centers from China, were prospectively recruited. The inclusion criteria were as follows: (1) all patients who were diagnosed with APE on computed tomography pulmonary angiography (CTPA) or pulmonary ventilation perfusion (V/Q) scan [13]; (2) those aged > 18 years; (3) and those with complete imaging and clinical data and informed consent.