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Oct 17, 2024 | 
thereader.mitpress.mit.edu | Alan Chodos |Christopher Mason |Erika Nesvold
BeeLine Reader uses subtle color gradients to help you read more efficiently. Neutrinos. They’re tiny, just points in space. Each one barely affects anything else. They pass through you, the Earth, and the sun with hardly a trace. They almost never reveal themselves, but without them we couldn’t know why the stars shine. Each has a minute mass. And while their individual interactions are meager, there are so many that, all together, they might change the courses of galaxies.
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Oct 15, 2024 | 
nature.com | JangKeun Kim |Francisco J. Enguita |Sylvain V Costes |Ryan Scott |Lauren Sanders |David Furman | +3 more
Correction to: Communications Biology https://doi.org/10.1038/s42003-024-06944-6, published online 05 October 2024In the Acknowledgement section, the L.I.G. was supported by the US Army Medical Research Command (award W81XWH2110402) was omitted. The original article has been corrected.
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Oct 4, 2024 | 
nature.com | JangKeun Kim |Francisco J. Enguita |Sylvain V Costes |Ryan Scott |Lauren Sanders |David Furman | +3 more
AbstractIn the era of renewed space exploration, comprehending the effects of the space environment on human health, particularly for deep space missions, is crucial. While extensive research exists on the impacts of spaceflight, there is a gap regarding female reproductive risks. We hypothesize that space stressors could have enduring effects on female health, potentially increasing risks for future pregnancies upon return to Earth, particularly related to small-for-gestational-age (SGA) fetuses.
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Aug 15, 2024 | 
nature.com | Binsheng Gong |Jean Thierry-Mieg |Todd Richmond |Rebecca Kusko |Wendell D. Jones |Weida Tong | +1 more
AbstractNext-generation sequencing (NGS) has revolutionized genomic research by enabling high-throughput, cost-effective genome and transcriptome sequencing accelerating personalized medicine for complex diseases, including cancer. Whole genome/transcriptome sequencing (WGS/WTS) provides comprehensive insights, while targeted sequencing is more cost-effective and sensitive.
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Jun 11, 2024 | 
nature.com | Henry Cope |Jonas Elsborg |Samuel Demharter |J. McDonald |Chiara Wernecke |Sigrid S. Reinsch | +11 more
AbstractSpaceflight poses a unique set of challenges to humans and the hostile spaceflight environment can induce a wide range of increased health risks, including dermatological issues. The biology driving the frequency of skin issues in astronauts is currently not well understood.
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Jun 11, 2024 | 
nature.com | Fei Wu |JangKeun Kim |Cem Meydan |Francine E Garrett-Bakelman |Nazish Sayed |Simon Melov | +4 more
AbstractMicrogravity is associated with immunological dysfunction, though the mechanisms are poorly understood. Here, using single-cell analysis of human peripheral blood mononuclear cells (PBMCs) exposed to short term (25 hours) simulated microgravity, we characterize altered genes and pathways at basal and stimulated states with a Toll-like Receptor-7/8 agonist.
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Jun 11, 2024 | 
nature.com | Christopher Mason |James Green |Jordan Baechle |Mathias Basner |Susan Bailey |Joseph Borg | +34 more
AbstractThe recent acceleration of commercial, private and multi-national spaceflight has created an unprecedented level of activity in low Earth orbit, concomitant with the largest-ever number of crewed missions entering space and preparations for exploration-class (lasting longer than one year) missions. Such rapid advancement into space from many new companies, countries and space-related entities has enabled a ‘second space age’.
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Jun 10, 2024 | 
nature.com | Keith Siew |Charlotte Nelson |Alessandra Grillo |Eliah G. Overbey |JangKeun Kim |Sanghee Yun | +41 more
AbstractMissions into Deep Space are planned this decade. Yet the health consequences of exposure to microgravity and galactic cosmic radiation (GCR) over years-long missions on indispensable visceral organs such as the kidney are largely unexplored.
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Jun 10, 2024 | 
nature.com | Fei Wu |JangKeun Kim |Eliah G. Overbey |Cem Meydan |Christopher Mason
AbstractTelomeres are repetitive nucleoprotein complexes at chromosomal termini essential for maintaining genome stability. Telomeric RNA, or TERRA, is a previously presumed long noncoding RNA of heterogeneous lengths that contributes to end-capping structure and function, and facilitates telomeric recombination in tumors that maintain telomere length via the telomerase-independent Alternative Lengthening of Telomeres (ALT) pathway.
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Jun 10, 2024 | 
nature.com | Jean Calleja-Agius |Joseph Borg |JangKeun Kim |Caroline Coffey |Nathaniel J. Szewczyk |Christopher Mason | +5 more
AbstractMounting ambitions and capabilities for public and private, non-government sector crewed space exploration bring with them an increasingly diverse set of space travelers, raising new and nontrivial ethical, legal, and medical policy and practice concerns which are still relatively underexplored.
