BDJ Team

2 days ago | nature.com | Ewen Callaway

If Stephen Quake gets his way, biologists in the future will spend a lot less time wielding pipettes. “Our goal,” he says, “is to create computational tools so that cell biology goes from being 90% experimental and 10% computational to the other way around.”Quake, head of science at the Chan Zuckerberg Initiative (CZI) in Redwood City, California, is among the researchers leading a charge to create virtual cells.

2 days ago | nature.com | Siân Anna Lewis

Microglia are the resident immune cells of the brain. However, under certain circumstances, other myeloid cells — including bone marrow-derived myeloid cells — can infiltrate the brain parenchyma. These cells, along with border-associated macrophages (BAMs), have important roles in immune surveillance and defence, but how they interact and enter the brain is poorly understood.

3 days ago | nature.com | Jeff Tollefson

Mary Rice was among hundreds of scientists at Harvard University who watched helplessly as millions of dollars in research funds disappeared in an instant in mid-May. Two of the pulmonologist’s grants were formally cancelled as part of a series of punitive actions taken by the administration of US President Donald Trump against the university. Little justification was given to Rice aside from a statement that her research does not align with government priorities.

3 days ago | nature.com | M. Teresa Villanueva

Chimeric antigen receptor (CAR)-T cells have revolutionized the treatment of haematological malignancies. However, challenges — such as relapse owing to insufficient persistence of CAR-T cells — remain. Now, writing in Science Translational Medicine, Bailey et al. have demonstrated that knocking out the interferon-gamma (IFN-γ) receptor (IFN-γR) in CAR-T cells enhances their efficacy and persistence in models of haematological and solid tumours.

3 days ago | nature.com | Benjamin Thompson |Shamini Bundell

Download the Nature Podcast 25 June 2025We’d like to learn more about our listeners, please help us out by filling in this short survey. In this episode:00:45 Is AI-research being co-opted to keep track of people? A significant amount of research in the AI field of computer vision is being used to analyse humans in ways that support the development of surveillance technologies, according to new research.