Nature Methods

Nature Methods is a scientific journal that is published monthly and focuses on innovative scientific techniques. Launched in 2004, it is produced by the Nature Publishing Group. Similar to other journals in the Nature family, it does not have an external editorial board; instead, an internal team handles editorial decisions. However, the review process includes peer evaluations by outside experts. As per the Journal Citation Reports, this journal achieved an impressive impact factor of 32.072 in 2014, placing it at the top of the "Biochemical Research Methods" category.

International, Trade/B2B

English

Journal

Outlet metrics

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Ranking

Global

#1719

United States

#1036

Science and Education/Biology

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Articles

Best practices for methylome characterization in novel species: a case study in the microalgae Microchloropsis - Communications Biology

2 days ago | nature.com | Christy Steadman |Eric Small

AbstractMicroalgae remain an important feedstock in the circular bioeconomy. The discovery of new species combined with advanced biotechnology drives optimization of performance predicated on deep knowledge of algal genomics and phenotype. Understanding the contribution of epigenetic processes to algal function provides insight and better approaches for achieving production goals.
Which programming language should I use? A guide for early-career researchers

2 days ago | nature.com | Jeffrey Perkel

Each year, the code-sharing platform GitHub releases its ‘State of the Octoverse’ report, which among other things ranks the popularity of programming languages. The latest report, released in October 2024, had some good news for pythonistas, as Python programmers are called: for the first time in ten years, the language JavaScript had been bumped from the top of the leader board and replaced by Python.
‘Dark matter’, 'Big Bang' and ‘spin’: how physics terms can confuse researchers

3 days ago | nature.com | Zeeya Merali

Listen to episode 3 of What's in a nameCategorizing things is central to science. And there are dozens of systems scientists have created to name everything from the trenches on the sea bed to the stars in the sky. But names have consequences. What’s in a name is a series exploring naming in science and how names impact the world.
Exclusive: a Nature analysis signals the beginnings of a US science brain drain

3 days ago | nature.com | Jack Leeming

Researchers in the United States are seeking career opportunities abroad as President Donald Trump’s administration slashes science funding and workforce numbers, finds an analysis of Nature’s jobs-board data. Data from the Nature Careers global science jobs platform show that US scientists submitted 32% more applications for jobs abroad between January and March 2025 than during the same period in 2024. At the same time, the number of US-based users browsing jobs abroad increased by 35%.
A radical approach to treating post-orgasmic illness syndrome: a correspondence - International Journal of Impotence Research

3 days ago | nature.com | Olivia Johnson

Post-Orgasmic Illness Syndrome (POIS) is a condition characterized by troubling symptoms following orgasm. Symptoms typically arise within 30 minutes of ejaculation and persist for up to 7 days [1]. Symptoms typically resolve spontaneously [2]. Five diagnostic criteria have been established, and include meeting at least one of seven symptom clusters. The seven symptom clusters are general, head, eyes, nose, throat, flu-like, and muscle [1].
Multi-omic and spatial analysis of mouse kidneys highlights sex-specific differences in gene regulation across the lifespan - Nature Genetics

4 days ago | nature.com | Wagma Caravan |Kazuhito Sato |Xiang Li |Yize Li |John Herndon |Maxim N. Artyomov | +1 more

AbstractThere is a sex bias in the incidence and progression of many kidney diseases. To better understand such sexual dimorphism, we integrated data from six platforms, characterizing 76 kidney samples from 68 mice at six developmental and adult time points, creating a molecular atlas of the mouse kidney across the lifespan for both sexes.
Career pathways, part 17 - Nature Metabolism

4 days ago | nature.com | Leah A Gates |Benjamin Weaver

Leah Gates and Ben Weaver reflect on how overcoming different hurdles and dealing with unexpected events has ultimately shaped their careers. They also emphasize the importance of relying on a strong support network.
The variability of Antarctic dense water overflows can be observed from space - Communications Earth & Environment

4 days ago | nature.com | Matthis Auger |Paul Spence |Adele K. Morrison

AbstractAround the margins of Antarctica, dense waters formed on the continental shelf are exported to oceanic depths. This overflow of dense waters to the abyss ventilates the ocean, and is vital to the global overturning circulation.
Brand-new colour created by tricking human eyes with laser

6 days ago | nature.com | Elizabeth Gibney

Five people have been able to perceive a colour never before seen by human eyes, after researchers used lasers and tracking technology to selectively activate certain cells in their retinas. The blue-greenish hue has an intensity, or ‘saturation’, outside the natural range of colours seen by humans. The work is “amazing technically” and an “extraordinary achievement”, says Kimberly Jameson, a colour-vision scientist at the University of California, Irvine.
‘Totally broken’: how Trump 2.0 has paralysed work at US science agencies

1 week ago | nature.com | Dan Garisto |Jeff Tollefson

As the administration of President Donald Trump continues its campaign to reshape the US government with spending cuts and mass lay-offs, some scientists still employed at government agencies say that their work has become impossible.